Protein Structure Prediction : A Practical Approach

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Release : 1996-11-28
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Book Rating : 997/5 ( reviews)

Protein Structure Prediction : A Practical Approach - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Structure Prediction : A Practical Approach write by Michael J. E. Sternberg. This book was released on 1996-11-28. Protein Structure Prediction : A Practical Approach available in PDF, EPUB and Kindle. The three-dimensional structure of proteins is a key factor in their biological activity. There is an increasing need to be able to predict the structure of a protein once its amino-acid sequence is known; this book presents practical methods of achieving that ambitious aim, using the latest computer modelling algorithms. - ;The prediction of the three-dimensional structure of a protein from its sequence is a problem faced by an ever-increasing number of biological scientists as they strive to utilize genetic information. The increasing sizes of the sequence and structural databases, the improvements in computing power, and the deeper understanding of the principles of protein structure have led to major developments in the field in the last few years. This book presents practical computer-based methods using the latest computer modelling algorithms. -

Protein Structure Prediction

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Release : 2008-02-03
Genre : Science
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Book Rating : 682/5 ( reviews)

Protein Structure Prediction - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Structure Prediction write by David Webster. This book was released on 2008-02-03. Protein Structure Prediction available in PDF, EPUB and Kindle. The number of protein sequences grows each year, yet the number of structures deposited in the Protein Data Bank remains relatively small. The importance of protein structure prediction cannot be overemphasized, and this volume is a timely addition to the literature in this field. Protein Structure Prediction: Methods and Protocols is a departure from the normal Methods in Molecular Biology series format. By its very nature, protein structure prediction demands that there be a greater mix of theoretical and practical aspects than is normally seen in this series. This book is aimed at both the novice and the experienced researcher who wish for detailed inf- mation in the field of protein structure prediction; a major intention here is to include important information that is needed in the day-to-day work of a research scientist, important information that is not always decipherable in scientific literature. Protein Structure Prediction: Methods and Protocols covers the topic of protein structure prediction in an eclectic fashion, detailing aspects of pred- tion that range from sequence analysis (a starting point for many algorithms) to secondary and tertiary methods, on into the prediction of docked complexes (an essential point in order to fully understand biological function). As this volume progresses, the authors contribute their expert knowledge of protein structure prediction to many disciplines, such as the identification of motifs and domains, the comparative modeling of proteins, and ab initio approaches to protein loop, side chain, and protein prediction.

Introduction to Protein Structure Prediction

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Release : 2011-03-16
Genre : Science
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Book Rating : 46X/5 ( reviews)

Introduction to Protein Structure Prediction - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Introduction to Protein Structure Prediction write by Huzefa Rangwala. This book was released on 2011-03-16. Introduction to Protein Structure Prediction available in PDF, EPUB and Kindle. A look at the methods and algorithms used to predict protein structure A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered: Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutant Whether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.

Protein Structure

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Release : 1997
Genre : Science
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Book Rating : 198/5 ( reviews)

Protein Structure - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Structure write by Thomas E. Creighton. This book was released on 1997. Protein Structure available in PDF, EPUB and Kindle. Protein Structure: A Practical Approach gives general methods for determining protein structure that will be very widely applicable, from the simple electrophoretic, chromatographic, and spectrophotometric techniques to the relatively more complex and sophisticated methods of mass spectrometry and ultracentrifugation. This second edition has been fully updated to embrace the most recent developments in the field, and will be invaluable to all involved in protein research.

Protein Structure Prediction

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Release : 2002
Genre : Science
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Book Rating : 775/5 ( reviews)

Protein Structure Prediction - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Structure Prediction write by Igor F. Tsigelny. This book was released on 2002. Protein Structure Prediction available in PDF, EPUB and Kindle.