Protein Surface Recognition by Designed Metal Complexes - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Surface Recognition by Designed Metal Complexes write by James Muldoon. This book was released on 2009. Protein Surface Recognition by Designed Metal Complexes available in PDF, EPUB and Kindle.
Protein Surface Recognition
Protein Surface Recognition - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Surface Recognition write by Ernest Giralt. This book was released on 2011-07-07. Protein Surface Recognition available in PDF, EPUB and Kindle. A new perspective on the design of molecular therapeutics is emerging. This new strategy emphasizes the rational complementation of functionality along extended patches of a protein surface with the aim of inhibiting protein/protein interactions. The successful development of compounds able to inhibit these interactions offers a unique chance to selectively intervene in a large number of key cellular processes related to human disease. Protein Surface Recognition presents a detailed treatment of this strategy, with topics including: an extended survey of protein-protein interactions that are key players in human disease and biology and the potential for therapeutics derived from this new perspective the fundamental physical issues that surround protein-protein interactions that must be considered when designing ligands for protein surfaces examples of protein surface-small molecule interactions, including treatments of protein-natural product interactions, protein-interface peptides, and rational approaches to protein surface recognition from model to biological systems a survey of techniques that will be integral to the discovery of new small molecule protein surface binders, from high throughput synthesis and screening techniques to in silico and in vitro methods for the discovery of novel protein ligands. Protein Surface Recognition provides an intellectual “tool-kit” for investigators in medicinal and bioorganic chemistry looking to exploit this emerging paradigm in drug discovery.
Peptide and protein surface recognition by tetraguanidinium compounds
Peptide and protein surface recognition by tetraguanidinium compounds - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peptide and protein surface recognition by tetraguanidinium compounds write by Xavier Salvatella i Giralt. This book was released on 2002. Peptide and protein surface recognition by tetraguanidinium compounds available in PDF, EPUB and Kindle.
Comprehensive Supramolecular Chemistry II
Comprehensive Supramolecular Chemistry II - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Comprehensive Supramolecular Chemistry II write by George W. Gokel. This book was released on 2017-06-22. Comprehensive Supramolecular Chemistry II available in PDF, EPUB and Kindle. Comprehensive Supramolecular Chemistry II, Second Edition, Nine Volume Set is a ‘one-stop shop’ that covers supramolecular chemistry, a field that originated from the work of researchers in organic, inorganic and physical chemistry, with some biological influence. The original edition was structured to reflect, in part, the origin of the field. However, in the past two decades, the field has changed a great deal as reflected in this new work that covers the general principles of supramolecular chemistry and molecular recognition, experimental and computational methods in supramolecular chemistry, supramolecular receptors, dynamic supramolecular chemistry, supramolecular engineering, crystallographic (engineered) assemblies, sensors, imaging agents, devices and the latest in nanotechnology. Each section begins with an introduction by an expert in the field, who offers an initial perspective on the development of the field. Each article begins with outlining basic concepts before moving on to more advanced material. Contains content that begins with the basics before moving on to more complex concepts, making it suitable for advanced undergraduates as well as academic researchers Focuses on application of the theory in practice, with particular focus on areas that have gained increasing importance in the 21st century, including nanomedicine, nanotechnology and medicinal chemistry Fully rewritten to make a completely up-to-date reference work that covers all the major advances that have taken place since the First Edition published in 1996
Protein Self-Assembly
Protein Self-Assembly - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Self-Assembly write by Jennifer J. McManus. This book was released on 2020-08-08. Protein Self-Assembly available in PDF, EPUB and Kindle. This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.
