Protein Therapeutics, 2 Volume Set - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Therapeutics, 2 Volume Set write by Tristan Vaughan. This book was released on 2017-12-04. Protein Therapeutics, 2 Volume Set available in PDF, EPUB and Kindle. Branchenführende Big-Pharma-Unternehmen und erstklassige Forscher präsentieren grundlegende Konzepte und Herausforderungen bei proteinbasierten Pharmazeutika. Beinhaltet auch eine Einführung in die aus Sicht der Arzneimittelentwicklung fünf wesentlichen Anwendungsbereiche.
Characterization of Protein Therapeutics using Mass Spectrometry
Characterization of Protein Therapeutics using Mass Spectrometry - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Characterization of Protein Therapeutics using Mass Spectrometry write by Guodong Chen. This book was released on 2014-07-08. Characterization of Protein Therapeutics using Mass Spectrometry available in PDF, EPUB and Kindle. This book highlights current approaches and future trends in the use of mass spectrometry to characterize protein therapies. As one of the most frequently utilized analytical techniques in pharmaceutical research and development, mass spectrometry has been widely used in the characterization of protein therapeutics due to its analytical sensitivity, selectivity, and specificity. This book begins with an overview of mass spectrometry techniques as related to the analysis of protein therapeutics, structural identification strategies, quantitative approaches, followed by studies involving characterization of process related protein drug impurities/degradants, metabolites, higher order structures of protein therapeutics. Both general practitioners in pharmaceutical research and specialists in analytical sciences will benefit from this book that details step-by-step approaches and new strategies to solve challenging problems related to protein therapeutics research and development.
Therapeutic Proteins
Therapeutic Proteins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Therapeutic Proteins write by Vladimir Voynov. This book was released on 2016-05-01. Therapeutic Proteins available in PDF, EPUB and Kindle. Emphasizing the newest developments in the field, this volume presents detailed methodswith added emphasison therapeutic protein discovery. It features key tips and valuable implementation advice to ensure successful results."
Protein Therapeutics
Protein Therapeutics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Therapeutics write by Tristan Vaughan. This book was released on 2017-07-28. Protein Therapeutics available in PDF, EPUB and Kindle. In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.
Therapeutic Proteins Against Human Diseases
Therapeutic Proteins Against Human Diseases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Therapeutic Proteins Against Human Diseases write by Fahmida Khatoon Zahid Balouch. This book was released on 2022-09-28. Therapeutic Proteins Against Human Diseases available in PDF, EPUB and Kindle. This book compiles updated research about the implications of therapeutic proteins in various human diseases. The initial chapters of the book provide basic information on the therapeutic proteins and discuss techniques for their formulation, production, and analytic approaches for their characterization. The subsequent chapters shed light on therapies based on therapeutic proteins against metabolic disorders, neurological disorders, cancer, autoimmune disorders, and infectious diseases. Importantly, it presents the factors influencing the immunogenicity of therapeutic proteins, including, genetic factors, disease type, and origin of therapeutic protein, dose frequency, administration route, and treatment duration. The book also reviews the strategies for reducing immunogenicity associated with therapeutic proteins, including PEGylation, site specific mutagenesis, exon shuffling, and humanizing of monoclonal antibodies. Further, it presents strategies for improving the typical drawback associated with protein therapeutics including instability and limited penetration through biological barriers. This book covers various computational methods that are commonly used for designing therapeutic proteins and in silico method for predicting and improving in vivo efficacy of the therapeutic molecules. Lastly, the book highlights the recent advances in developing nanosized delivery systems to improve safety and efficacy of protein therapeutics. This book caters to students and researchers of medicinal chemistry, pharmaceutical sciences and therapeutics. It is also useful to clinicians working with therapeutic proteins.
