Psychiatric Genetics and Genomics

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Release : 2004-09-23
Genre : Medical
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Book Rating : 867/5 ( reviews)

Psychiatric Genetics and Genomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Psychiatric Genetics and Genomics write by Peter McGuffin. This book was released on 2004-09-23. Psychiatric Genetics and Genomics available in PDF, EPUB and Kindle. From reviews of the hardback:'It is timely to see such an excellent textbook... Aimed at graduate level students, this book is complex enough to be thorough, but clear with enough background to be accessible... the coverage is comprehensive and the flow logical... The text is uniformly well written and achieves a successful integration.' -The Lancet'A good introduction and reference book for professionals interested in psychiatric genetics such as psychiatrists, clinical psychologists and neuroscientists... the book you want to have on your bookshelf to look up material and obtain a complete and balanced picture of the field.' -Psychological MedicineRevised for paperback edition, with new appendicesGenetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations.The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults. This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future.The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors.Readership: Psychiatrists, clinical psychologists, geneticists, neuroscientists and neurologists

Psychiatric Genomics

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Release : 2022-03-18
Genre : Medical
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Book Rating : 007/5 ( reviews)

Psychiatric Genomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Psychiatric Genomics write by Evangelia Eirini Tsermpini. This book was released on 2022-03-18. Psychiatric Genomics available in PDF, EPUB and Kindle. **Selected for Doody's Core TitlesĀ® 2024 in Clinical Genetics** Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation. After providing an introduction to genomics and psychiatry, international experts discuss the genomic basis of schizophrenia, bipolar disorder, depression, personality disorders, anxiety disorders, addictions, eating disorders, and sleep disorders, among other disorders. In addition, recommendations for next steps in clinical implementation and drug discovery are discussed in-depth, with chapters dedicated to pharmacogenomics and antipsychotics, antidepressants and mood stabilizers, adverse drug reactions, implementation of pharmacogenomics in psychiatric clinics, and ethical issues. Finally, methods sections provide a solid grounding in research approaches and computational analytics, from using animal models in psychiatric genomics and accessing biobanks, to employing computational analysis, genome-wide association studies (GWAS), brain pathophysiology, and endophenotypes in psychiatric research. - Thoroughly examines the genetic mechanisms underlying a broad range of psychiatric disorders - Offers genomic methodologies and analytical approaches supporting new research and clinical translation, including personalized diagnosis and treatment models - Features chapter contributions from international leaders in the field

Psychiatric Genetics

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Release : 2018
Genre : Medical
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Book Rating : 976/5 ( reviews)

Psychiatric Genetics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Psychiatric Genetics write by Thomas G. Schulze. This book was released on 2018. Psychiatric Genetics available in PDF, EPUB and Kindle. Psychiatric Genetics: A Primer for Clinical and Basic Scientists offers a straightforward introduction to the essentials of psychiatric genetics, covering basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic studies, statistical genetics, bioinformatics and genomics, pharmacogenetics, the most relevant animal models, and biobanking. Each chapter begins with a list of "take home" points that summarizes content, followed by a brief overview of current knowledge and suggestions for further reading.

Research Advances in Genetics and Genomics

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Release : 2007-05-03
Genre : Medical
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Book Rating : 100/5 ( reviews)

Research Advances in Genetics and Genomics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Research Advances in Genetics and Genomics write by Nancy C. Andreasen. This book was released on 2007-05-03. Research Advances in Genetics and Genomics available in PDF, EPUB and Kindle. Research Advances in Genetics and Genomics: Implications for Psychiatry introduces mental health professionals to exciting breakthroughs in endophenotypes, animal models, microarrays, and genetic mapping, as well as general strategies for identifying the genetic mechanisms of mental illnesses. Uniquely valuable both as summary and signpost, this concise volume provides a fascinating overview of recent cutting-edge developments in the application of molecular genetics, genomics, and proteomics to the study of psychiatric populations. By reading Research Advances in Genetics and Genomics, you will gain a better understanding of Psychiatric Genetics -- Reviews and assesses the major research paradigms that have emerged in the field of psychiatric genetics over the several past decades, exploring the major conceptual and philosophical issues they pose and the value of their integration. Molecular Structure of Nucleic Acids -- An overview of the double-helix discovery and provides a context for current endeavors, the original one-page April 1953 Nature paper by Watson and Crick, which sparked a revolution in the life sciences. Psychiatry in the Genomics Era -- Posits that one of the most important consequences of genomics will be the development of individualized treatments that allow a clinician to tailor therapy on the basis of the unique genotype of each patient rather than on the mean responses of groups of unrelated patients. The Genomics Revolution -- Details the implications of the genome for future medical practice, including the potential for developing methods and tools to better understand, treat, and prevent major mental disorders. The Endophenotype Concept in Psychiatry -- Explains the etymology and strategy behind the use of endophenotypes in neuropsychiatric research and, more generally, in research on other diseases with complex genetics, such as schizophrenia. The Genes and Brains of Mice and Men -- Shows why a detailed assessment of brain function in mice is so important for advancing psychiatric research in humans. Humans and mice share numerous features-in fact, for an estimated 99% of human genes a mouse version may be identified-of brain organization and behavioral responses to many pharmacological agents. Microarray Technology -- Asserts that microarrays present a methodology for identifying genes or pathways for new and unique potential drug targets, determining premorbid diagnosis, predicting drug responsiveness for individual patients, and, eventually, initiating gene therapy and prevention strategies. Meticulously referenced, this volume is exceptionally useful as a starting point for understanding the impact of genetics and genomics on psychiatry, serving to introduce psychiatrists, psychologists, neurologists, and geneticists to this exciting field.

Principles of Psychiatric Genetics

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Release : 2012-09-13
Genre : Medical
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Book Rating : 495/5 ( reviews)

Principles of Psychiatric Genetics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Principles of Psychiatric Genetics write by John I. Nurnberger. This book was released on 2012-09-13. Principles of Psychiatric Genetics available in PDF, EPUB and Kindle. A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.