Recent Advances in the use of Drosophila in Neurobiology and Neurodegeneration

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Release : 2011-09-07
Genre : Medical
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Book Rating : 194/5 ( reviews)

Recent Advances in the use of Drosophila in Neurobiology and Neurodegeneration - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Recent Advances in the use of Drosophila in Neurobiology and Neurodegeneration write by . This book was released on 2011-09-07. Recent Advances in the use of Drosophila in Neurobiology and Neurodegeneration available in PDF, EPUB and Kindle. Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Insights into Human Neurodegeneration: Lessons Learnt from Drosophila

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Release : 2019-12-05
Genre : Medical
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Book Rating : 18X/5 ( reviews)

Insights into Human Neurodegeneration: Lessons Learnt from Drosophila - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Insights into Human Neurodegeneration: Lessons Learnt from Drosophila write by Mousumi Mutsuddi. This book was released on 2019-12-05. Insights into Human Neurodegeneration: Lessons Learnt from Drosophila available in PDF, EPUB and Kindle. This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from Drosophila model, in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions. Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from Drosophila about Alzheimer's, Parkinson’s, Spinomuscular Atrophy, Huntington’s diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of Drosophila for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered here will not only be relevant for beginners who are new to the concept of the extensive utility of Drosophila as a model to study human disorders; but will also be an important contribution to the scientific community, with an insight into the paradigm shift in our understanding of neurodegenerative disorders. Completed with informative tables and communicative illustrations this book will keep the readers glued and intrigued. We have comprehensively anthologized the lessons learnt on neurodegeneration from Drosophila and have thus provided an insight into the multidimensional aspects of pathogenicities of majority of the neurodegenerative disorders.

Advances in Research on Neurodegeneration

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Release : 2013-04-09
Genre : Medical
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Book Rating : 435/5 ( reviews)

Advances in Research on Neurodegeneration - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Advances in Research on Neurodegeneration write by R. Horowski. This book was released on 2013-04-09. Advances in Research on Neurodegeneration available in PDF, EPUB and Kindle. The 10th International Winter Conference on Neurodegeneration (lWCN) has taken place from February 14-16,2002, at the lovely "SchloB Ziethen", an old prussian manor (in Prussia, 'faute de mieux', called 'SchloB', i. e. cas tle or residence). This place is 20 km off Tegel Airport, Berlin's main airport, and has been beautifully restored by baroness Edith von Thiingen (nee von BUlow, i. e. of historical Prussian aristocracy); it lends itself rather perfectly for the IWCN type of small interdisciplinary workshops on neurodegenera tion which combine short lectures with plenty of discussion. In this context, we could quote Alexander von Humboldt's famous opening words for one of the first international scientific meetings held at Berlin, on September 18, 1828: "The main purpose ... does not consist in a mutual reading of manuscripts all to be printed after at least one year in specialised publications, but in the personal communication amongst those who work in similar scientific fields; the oral and thus more stimulating exchange of ideas, might they represent facts, opinions or doubts; the foundation of friendly relations which convey illumination to our sciences, serene grace to our lives and tolerance and mildness to our habits ... Berlin, Sept. 18, 1828 Alexander von Humboldt To the IWCN aficionado, it may come as a little surprise that this is the pub lication of the 10th Winter Conference as this might mean that they must have missed number 9.

Drosophila melanogaster

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Release : 2018-02-28
Genre : Technology & Engineering
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Book Rating : 537/5 ( reviews)

Drosophila melanogaster - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Drosophila melanogaster write by Farzana Khan Perveen. This book was released on 2018-02-28. Drosophila melanogaster available in PDF, EPUB and Kindle. This book contains 12 chapters divided into two sections. Section 1 is "Drosophila - Model for Genetics." It covers introduction, chromosomal polymorphism, polytene chromosomes, chromosomal inversion, chromosomal evolution, cell cycle regulators in meiosis and nongenetic transgenerational inheritance in Drosophila. It also includes ecological genetics, wild-type strains, morphometric analysis, cytostatics, frequencies of early and late embryonic lethals (EEL and LEL) and mosaic imaginal discs of Drosophila for genetic analysis in biomedical research. Section 2 is "Drosophila - Model for Therapeutics." It explains Drosophila as model for human diseases, neurodegeneration, heart-kidney metabolic disorders, cancer, pathophysiology of Parkinson's disease, dopamine, neuroprotective therapeutics, mitochondrial dysfunction and translational research. It also covers Drosophila role in ubiquitin-carboxyl-terminal hydrolase-L1 (UCH-L1) protein, eye development, anti-dUCH antibody, neuropathy target esterase (NTE), organophosphorous compound-induced delayed neuropathy (OPIDN) and hereditary spastic paraplegia (HSP). It also includes substrate specificities, kinetic parameters of recombinant glutathione S-transferases E6 and E7 (DmGSTE6 and DmGSTE7), detoxification and insecticidal resistance and antiviral immunity in Drosophila.

Development and Neurobiology of Drosophila

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Release : 2013-11-11
Genre : Science
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Book Rating : 687/5 ( reviews)

Development and Neurobiology of Drosophila - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Development and Neurobiology of Drosophila write by O. Siddiqi. This book was released on 2013-11-11. Development and Neurobiology of Drosophila available in PDF, EPUB and Kindle. There is no multicellular animal whose genetics is so well understood as Drosophila melanogaster. An increasing number of biologists have, therefore, turned to the fruitfly in pursuit of such diverse areas as the molecular biology of eukaryotic cells, development and neurobiology. Indeed there are signs that Dro sophila may soon become the most central organism in biqlogy for genetic analysis of complex problems. The papers in this collection were presented at a conference on Development and Behavior of Drosophila held at the Tata Insti tute of Fundamental Research from 19th to 22nd December, 1979. The volume reflects the commonly shared belief of the participants that Drosophila has as much to contribute to biology in the future as it has in the past. We hope it will be of interest not merely to Dro sophilists but to all biologists. We thank Chetan Premani, Anil Gupta, K.S. Krishnan, Veronica Rodrigues, Hemant Chikermane and K. Vijay Raghavan for help with recording and transcription of the proceedings and Vrinda Nabar and K.V. Hareesh for editorial assistance. We thank Samuel Richman, Thomas Schmidt-Glenewinkel and T.R. Venkatesh for their valuable assistance in proofreading the manuscripts, and we also thank Patricia Rank for her excellent effort in the preparation of the final manuscripts. The conference was supported by a grant from Sir Dorabji Tata Trust.