Redox Signaling and Regulation in Biology and Medicine

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Release : 2009-05-06
Genre : Science
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Book Rating : 596/5 ( reviews)

Redox Signaling and Regulation in Biology and Medicine - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Redox Signaling and Regulation in Biology and Medicine write by Claus Jacob. This book was released on 2009-05-06. Redox Signaling and Regulation in Biology and Medicine available in PDF, EPUB and Kindle. This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way. Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.

Redox Signaling

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Release : 2024-08-01
Genre : Science
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Book Rating : 453/5 ( reviews)

Redox Signaling - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Redox Signaling write by . This book was released on 2024-08-01. Redox Signaling available in PDF, EPUB and Kindle. Advances in Cancer Research, Volume 162 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the ACR series Updated release includes the latest information on the Advances in Cancer Research

Redox Regulation of Differentiation and De-differentiation

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Release : 2021-08-26
Genre : Science
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Book Rating : 385/5 ( reviews)

Redox Regulation of Differentiation and De-differentiation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Redox Regulation of Differentiation and De-differentiation write by Carsten Berndt. This book was released on 2021-08-26. Redox Regulation of Differentiation and De-differentiation available in PDF, EPUB and Kindle. Cell differentiation and the development of multicellular organisms are processes of self-assembly, controlled and driven by signaling molecules and cascades including redox regulation. These reactions may have provided the energy for the first metabolic steps in the evolution of life. Today, redox modifications are established as important regulatory events in cellular functions including differentiation and development. Redox modifications of single cysteines regulate differentiation of stem cells, formation of functioning organs, and de-differentiation such as formation of cancer cells. Current cancer therapy is based on redox events as well and regeneration often reactivates developmental pathways. Understanding differentiation and de-differentiation on a molecular level is therefore a prerequisite for the continuing development of new medical therapies. This book summarizes the roles of redox regulation in development by bringing together different concepts and comparing similarities and differences between various cell types and species. An international team of contributors presents several new aspects of redox-regulated differentiation and de-differentiation, including aspects of redox medicine. Key Features Provides the first summary on this important topic Reviews redox-dependent development of model organisms and single organs Highlights the redox-regulated pathways important for differentiation processes Illustrates the potential of redox medicine Combines state-of-the-art knowledge in differentiation/development, aging/longevity, and repair/regeneration Written by leading experts in the field Related Titles Ayyanathan, K., ed. Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer (ISBN 978-1-77188-067-1) Clarke, M. & J. Frampton. Stem Cells: Biology and Application (ISBN 9780-8153-4511-4) Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Wong, E., ed. Autophagy and Signaling (ISBN 978-0-367-65772-7)

Oxidative Stress and Redox Regulation

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Release : 2013-03-15
Genre : Science
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Book Rating : 875/5 ( reviews)

Oxidative Stress and Redox Regulation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Oxidative Stress and Redox Regulation write by Ursula Jakob. This book was released on 2013-03-15. Oxidative Stress and Redox Regulation available in PDF, EPUB and Kindle. Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.

Peroxiporins

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Release : 2023-10-11
Genre : Science
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Book Rating : 784/5 ( reviews)

Peroxiporins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Peroxiporins write by Iria Medraño-Fernandez. This book was released on 2023-10-11. Peroxiporins available in PDF, EPUB and Kindle. To produce energy, aerobic organisms transform oxygen molecules into water. This reductive mechanism yields toxic radical intermediates, collectively known as reactive oxygen species (ROS). Paradoxically, these physiological processes entail the production of potentially damaging species. Evolution has turned this apparent disadvantage into an opportunity for transmitting information. As a result, redox signaling within the cell is an efficient exquisitely organized process. A key element for its regulation is the physical separation of sources and targets into different cell compartments. Peroxiporins, H2O2 transporting proteins spanning biological membranes, distribute the signal from emitters to receptors. Thus, these channels are strategically situated in the thin line between life and death, guaranteeing adequate but safe signaling. Key Features: - Provides a brief history of the discovery and characterization of peroxiporins - Reviews key findings on hydrogen peroxide transport across biological membranes - Discusses the cartography of redox signaling in crowded cells - Includes lavish illustrations and comprehensive images to facilitate teaching - Highlights recent findings, outstanding controversies and open questions