Insights into Regulatory B Cells - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Insights into Regulatory B Cells write by Yiwei Chu. This book was released on 2022-05-09. Insights into Regulatory B Cells available in PDF, EPUB and Kindle.
Molecular Biology of B Cells
Molecular Biology of B Cells - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Biology of B Cells write by Tasuku Honjo. This book was released on 2014-12-22. Molecular Biology of B Cells available in PDF, EPUB and Kindle. Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
B Cells in Immunity and Tolerance
B Cells in Immunity and Tolerance - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook B Cells in Immunity and Tolerance write by Ji-Yang Wang. This book was released on 2021-05-07. B Cells in Immunity and Tolerance available in PDF, EPUB and Kindle. This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
B Cell Receptor Signaling
B Cell Receptor Signaling - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook B Cell Receptor Signaling write by Tomohiro Kurosaki. This book was released on 2015-12-26. B Cell Receptor Signaling available in PDF, EPUB and Kindle. This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Regulatory B Cells
Regulatory B Cells - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Regulatory B Cells write by Gaetano Vitale. This book was released on 2014. Regulatory B Cells available in PDF, EPUB and Kindle. Annotation Regulatory B Cells: Methods and Protocols present the current experimental set-ups and methodologies useful for the identification and characterization of B cells with suppressive functions and for the study of their biological and immunological properties. Organized into four sections, this detailed volume covers the basic methods for the isolation and immunophenotypical characterization of specific B cell subsets from mouse and human tissues, methods for the investigation of the mechanisms of immune suppression operated by B cells, several experimental approaches for the ex vivo generation/expansion of IL-10-producing B cells, as well as procedures for the study of the immune suppressive function of B cells in specific pathological settings. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Regulatory B Cells: Methods and Protocols serves as an ideal guide for immunologists as well as for cell and molecular biologists interested in the intricacies of B cell biology.
