Resistance to Targeted Therapies in Breast Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Resistance to Targeted Therapies in Breast Cancer write by Jenifer R. Prosperi. This book was released on 2017-12-04. Resistance to Targeted Therapies in Breast Cancer available in PDF, EPUB and Kindle. We present an in-depth description of resistance to targeted therapies in breast cancer. Targeted therapies discussed here include those used to treat ER+ or Her2+ breast cancers (i.e., Tamoxifen or trastuzumab) or those targeting signaling pathways aberrantly activated in triple negative breast cancer (i.e., EGFR and Wnt signaling). We have also provided an overview of standard of care as an introduction into the importance of targeted therapy. It is our hope that this volume gives an insight into the landscape of breast cancer treatment, the challenges of targeted therapy, and a glimpse into the future of breast cancer therapy.
Targeted Therapies in Breast Cancer
Targeted Therapies in Breast Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Targeted Therapies in Breast Cancer write by Gw Sledge. This book was released on 2012-06. Targeted Therapies in Breast Cancer available in PDF, EPUB and Kindle. This new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.
Targeted Therapies in Oncology, Second Edition
Targeted Therapies in Oncology, Second Edition - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Targeted Therapies in Oncology, Second Edition write by Giuseppe Giaccone. This book was released on 2013-10-21. Targeted Therapies in Oncology, Second Edition available in PDF, EPUB and Kindle. Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted therapies and progress into future anticancer treatments. These therapies notably include: Targeted agents of immune checkpoints Signal-transduction inhibitors Antiangiogenic agents Vascular-disrupting agents Apoptosis modulators Stem cell inhibitors Tumor profiling for drug development The book emphasizes the biology behind this new class of drugs as well as the clinical achievements obtained. The contributors to this volume stand at the cutting edge of cancer research and treatment around the world.
Current Applications for Overcoming Resistance to Targeted Therapies
Current Applications for Overcoming Resistance to Targeted Therapies - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Current Applications for Overcoming Resistance to Targeted Therapies write by Myron R. Szewczuk. This book was released on 2019-07-15. Current Applications for Overcoming Resistance to Targeted Therapies available in PDF, EPUB and Kindle. Targeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. However, the development of resistance to these combinatorial approaches has led to the reassessment of currently available therapeutic options to overcome resistance to targeted therapy. This book aims to provide an update on the advancements in the therapeutic arms race between cancer, clinicians and scientists alike to overcome resistance to targeted therapies. Subject experts provide a comprehensive overview of the challenges and solutions to resistance to several conventional targeted therapies in addition to providing a discussion on broad topics including targeting components of the tumor microenvironment, emerging therapeutic options, and novel areas to be explored concerning nanotechnology and the epigenome.
Breast Cancer Metastasis and Drug Resistance
Breast Cancer Metastasis and Drug Resistance - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Breast Cancer Metastasis and Drug Resistance write by Aamir Ahmad. This book was released on 2019-08-27. Breast Cancer Metastasis and Drug Resistance available in PDF, EPUB and Kindle. Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
