Responsible Research with Biological Select Agents and Toxins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Responsible Research with Biological Select Agents and Toxins write by National Research Council. This book was released on 2010-02-12. Responsible Research with Biological Select Agents and Toxins available in PDF, EPUB and Kindle. The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.
Responsible Research with Biological Select Agents and Toxins
Responsible Research with Biological Select Agents and Toxins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Responsible Research with Biological Select Agents and Toxins write by National Research Council. This book was released on 2010-01-12. Responsible Research with Biological Select Agents and Toxins available in PDF, EPUB and Kindle. The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.
Biotechnology Research in an Age of Terrorism
Biotechnology Research in an Age of Terrorism - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Biotechnology Research in an Age of Terrorism write by National Research Council. This book was released on 2004-03-02. Biotechnology Research in an Age of Terrorism available in PDF, EPUB and Kindle. In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or transforming them into even more lethal forms. Policymakers and the scientific community at large must put forth a vigorous and immediate response to this challenge. This new book by the National Research Council recommends that the government expand existing regulations and rely on self-governance by scientists rather than adopt intrusive new policies. One key recommendation of the report is that the government should not attempt to regulate scientific publishing but should trust scientists and journals to screen their papers for security risks, a task some journals have already taken up. With biological information and tools widely distributed, regulating only U.S. researchers would have little effect. A new International Forum on Biosecurity should encourage the adoption of similar measures around the world. Seven types of risky studies would require approval by the Institutional Biosafety Committees that already oversee recombinant DNA research at some 400 U.S. institutions. These "experiments of concern" include making an infectious agent more lethal and rendering vaccines powerless.
Dual Use Research of Concern in the Life Sciences
Dual Use Research of Concern in the Life Sciences - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Dual Use Research of Concern in the Life Sciences write by National Academies of Sciences, Engineering, and Medicine. This book was released on 2017-10-01. Dual Use Research of Concern in the Life Sciences available in PDF, EPUB and Kindle. The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.
The Comprehensive Sourcebook of Bacterial Protein Toxins
The Comprehensive Sourcebook of Bacterial Protein Toxins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Comprehensive Sourcebook of Bacterial Protein Toxins write by Joseph E. Alouf. This book was released on 2005-12-20. The Comprehensive Sourcebook of Bacterial Protein Toxins available in PDF, EPUB and Kindle. This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. - Edited by two of the most highly regarded experts in the field from the Institut Pasteur, France - 14 brand new chapters dedicated to coverage of historical and general aspects of toxinology - Includes the major toxins of both basic and clinical interest are described in depth - Details applied aspects of toxins such as therapy, vaccinology, and toolkits in cell biology - Evolutionary and functional aspects of bacterial toxins evaluated and summarized - Toxin applications in cell biology presented - Therapy (cancer therapy, dystonias) discussed - Vaccines (native and genetically engineered vaccines) featured - Toxins discussed as biological weapons, comprising chapters on anthrax, diphtheria, ricin etc.
