Ribonucleases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ribonucleases write by Allen W. Nicholson. This book was released on 2001. Ribonucleases available in PDF, EPUB and Kindle.
Ribonucleases
Ribonucleases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ribonucleases write by Giuseppe D'Alessio. This book was released on 1997-02-11. Ribonucleases available in PDF, EPUB and Kindle. Pancreatic ribonuclease, the focus of highly productive scientific research for more than half a century and the only enzyme to be the basis of four Nobel prizes, has recently undergone a resurgence in popularity for the recognition of an extended ribonuclease superfamily with functions ranging from tumour growth and inhibition to self-recognition and neurotoxicity. This volume highlights the functional diversity of ribonucleases and reveals the emerging research opportunities provided by these enzymes.* Never before has discussion of the entire family of ribonucleases and related enzymes been covered in a single volume* Core chapters focus on the latest structures and functions of pancreatic-type ribonucleases* Structures and functions of intracellular ribonucleases and nondigestive members of the family are also covered* How ribonucleases continue to serve as excellent systems with which to uncover the secrets of protein chemistry is demonstrated
Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications
Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications write by . This book was released on 2001-09-28. Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications available in PDF, EPUB and Kindle. This second volume on ribonucleases provides up-to-date, methods-related information on these enzymes. Of particular interest to researchers will be the discussion of artificial and engineered ribonucleases, as well as the application of ribonucleases in medicine and biotechnology.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Ribonucleases
Ribonucleases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ribonucleases write by Allen W. Nicholson. This book was released on 2011-10-06. Ribonucleases available in PDF, EPUB and Kindle. Ribonucleases are a ubiquitous and functionally diverse group of enzymes that have a common ability to cleave RNA. Either through scission of internal phosphodiesters, or removal of nucleotides from RNA 5’ or 3’ ends, ribonucleases perform essential roles in gene expression and regulation, genome replication and maintenance, host defense, stress response, and viral strategies of infection. Ribonucleases have also served as highly informative models to understand virtually every aspect of biomolecular structure and function. The fifteen chapters in this volume are written by recognized researchers in the field, and provide in-depth analyses of the major ribonuclease families. Particular focus is given to the relation of ribonuclease structure and mechanism to biological function, as well as ribonuclease dysfunction in certain disease states. Other topics include the evolutionary genetics and functional diversification of ribonucleases, engineered ribonucleases as anti-cancer agents, the mechanisms of action of artificial ribonucleases, and ribonucleases as models to understand protein folding and stability. This volume should serve as an essential reference for a broad range of researchers and educators with interests in RNA metabolism, enzymology, and gene regulation.
RNA Damage and Repair
RNA Damage and Repair - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook RNA Damage and Repair write by Ioly Kotta-Loizou. This book was released on 2021-07-04. RNA Damage and Repair available in PDF, EPUB and Kindle. Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DNA), where genetic information is stored, and proteins, which perform the necessary functions within the cell. Traditionally, the structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also involved in catalysis and small RNAs regulate key cellular processes, such as cell growth, division, differentiation, aging and death. RNA is a sensitive macromolecule that can be easily damaged by environmental conditions (ultraviolet radiation, oxidative stress) and biological factors (ribonucleases, ribotoxins, CRISPR-Cas systems). Therefore, cells have developed mechanisms to protect and/or repair RNA molecules. This book presents an overview of the biology of RNA damage, protection and repair in prokaryotes and eukaryotes. Individual chapters cover the expression regulation, enzymology and physiological role of such systems, and link them to important human diseases such as cancer and degenerative diseases.
