Ribonucleases, Part A: Functional Roles and Mechanisms of Action - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ribonucleases, Part A: Functional Roles and Mechanisms of Action write by . This book was released on 2001-09-26. Ribonucleases, Part A: Functional Roles and Mechanisms of Action available in PDF, EPUB and Kindle. This first of two volumes provides up-to-date, methods-related information on ribonuclease functions, assays, and applications. Chapter topics include the identification of, characterization of, and assays for secreted ribonucleases; viral ribonucleases, artificial and engineered ribonucleases, and ribozymes.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Ribonucleases
Ribonucleases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ribonucleases write by Allen W. Nicholson. This book was released on 2001. Ribonucleases available in PDF, EPUB and Kindle.
Ribonucleases
Ribonucleases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ribonucleases write by Giuseppe D'Alessio. This book was released on 1997-02-11. Ribonucleases available in PDF, EPUB and Kindle. Pancreatic ribonuclease, the focus of highly productive scientific research for more than half a century and the only enzyme to be the basis of four Nobel prizes, has recently undergone a resurgence in popularity for the recognition of an extended ribonuclease superfamily with functions ranging from tumour growth and inhibition to self-recognition and neurotoxicity. This volume highlights the functional diversity of ribonucleases and reveals the emerging research opportunities provided by these enzymes.* Never before has discussion of the entire family of ribonucleases and related enzymes been covered in a single volume* Core chapters focus on the latest structures and functions of pancreatic-type ribonucleases* Structures and functions of intracellular ribonucleases and nondigestive members of the family are also covered* How ribonucleases continue to serve as excellent systems with which to uncover the secrets of protein chemistry is demonstrated
Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications
Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications write by . This book was released on 2001-09-28. Ribonucleases, Part B: Artificial and Engineered Ribonucleases and Speicifc Applications available in PDF, EPUB and Kindle. This second volume on ribonucleases provides up-to-date, methods-related information on these enzymes. Of particular interest to researchers will be the discussion of artificial and engineered ribonucleases, as well as the application of ribonucleases in medicine and biotechnology.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Artificial Nucleases
Artificial Nucleases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Artificial Nucleases write by Marina A. Zenkova. This book was released on 2004-01-07. Artificial Nucleases available in PDF, EPUB and Kindle. The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway in the course of different biochemical processes in the cell. A different pathway is used by some antibiotics which cleave DNA via redox-based mechanisms resulting in oxidative damage of nucleotide units and breakage of the DNA backbone. The above molecules are indispensable tools for manipulating nucleic acids and processing RNA; DNA-cleaving antibiotics and cytotoxic ribonucleases have demonstrated utility as chemotherapeutic agents. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. A dif ferent approach, in vitro selection, was also used to create artificial RNA and DNA enzymes capable of cleaving RNA. Being less efficient and specific as compared to the natural enzymes, the primitive mimics are smaller and robust and can function in a broad range of conditions.
