RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways write by Lynne E. Maquat. This book was released on 2011-09-02. RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways available in PDF, EPUB and Kindle. Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. - Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway - Expert researchers introduce the most advanced technologies and techniques - Offers step-by-step lab instructions, including necessary equipment and reagents
Nuclear-Cytoplasmic Transport
Nuclear-Cytoplasmic Transport - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Nuclear-Cytoplasmic Transport write by Weidong Yang. This book was released on 2018-07-27. Nuclear-Cytoplasmic Transport available in PDF, EPUB and Kindle. Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.
RNA Exosome
RNA Exosome - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook RNA Exosome write by Torben Heick Jensen. This book was released on 2011-06-29. RNA Exosome available in PDF, EPUB and Kindle. The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.
Laboratory Methods in Enzymology: RNA
Laboratory Methods in Enzymology: RNA - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Laboratory Methods in Enzymology: RNA write by Jon Lorsch. This book was released on 2013-09-11. Laboratory Methods in Enzymology: RNA available in PDF, EPUB and Kindle. Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on RNA, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes. - Indispensable tool for the researcher - Carefully written and edited by experts to contain step-by-step protocols - In this volume we have brought together a number of core protocols concentrating on RNA
RNA Helicases
RNA Helicases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook RNA Helicases write by Eckhard Jankowsky. This book was released on 2012-06-22. RNA Helicases available in PDF, EPUB and Kindle. This work integrates the current knowledge about RNA helicases from diverse fields ranging from cell and developmental biology to mechanistic enzymology and structural biology into one useful resource.
