Selectivity and Detectability Optimizations in HPLC - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Selectivity and Detectability Optimizations in HPLC write by Satinder Ahuja. This book was released on 1989-06-06. Selectivity and Detectability Optimizations in HPLC available in PDF, EPUB and Kindle. High Performance Liquid Chromatography Edited by Phyllis Brown and Richard Hartwick This contributed volume is designed to consolidate the basic theories of chromatography along with the more exciting developments in the field. This monograph addresses some questions that concern researchers in separation science, including: what is the current state of the art in liquid chromatography; has the development of liquid chromatography plateaued; if so, what new methods will take its place or complement it; and if not, where will the new frontiers be and what direction will liquid chromatography take? 1989 (0 471-84506-X) 688 pp. Quantitative Structure-Chromatographic Retention Relationships R. Kaliszan Written by a pioneer in the field, this book extends and updates research on quantitative structure retention relationships by consolidating and critically reviewing the extensive literature on the subject, while also providing the basic theoretical and practical information required in all investigations involving chromatography, analytical chemistry, biochemistry, and pharmaceutical research. Among the topics covered are the nature of chromatographic interactions, molecular interpretation of distribution processes in chromatography, topological indices as retention descriptors, and multiparameter structure-chromatographic retention relationships. 1987 (0 471-85983-4) 303 pp. Detectors for Liquid Chromatography Edited by Edward S. Yeung With its singular coverage of this fast-growing field, Detectors for Liquid Chromatography presents the state of the art in this subject area. It offers a comprehensive examination of the basic principles behind the detector response, instrumentation, and selected applications for comparison and evaluation of potential. Specifically, topics given in-depth coverage include polarimetric, indirect absorbance, refractive index detectors, absorption detectors for HPLC, FTIR and fluorometric detection, detection based on electrical and electromechanical measurements, and mass spectroscopy as an on-line detector for HPLC. 1986 (0 471-82169-1) 366 pp.
HPLC Method Development for Pharmaceuticals
HPLC Method Development for Pharmaceuticals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook HPLC Method Development for Pharmaceuticals write by Satinder Ahuja. This book was released on 2011-09-21. HPLC Method Development for Pharmaceuticals available in PDF, EPUB and Kindle. High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. - Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory - Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) - Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase
Modern Supercritical Fluid Chromatography
Modern Supercritical Fluid Chromatography - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Modern Supercritical Fluid Chromatography write by Larry M. Miller. This book was released on 2019-12-12. Modern Supercritical Fluid Chromatography available in PDF, EPUB and Kindle. Explains why modern supercritical fluid chromatography (SFC) is the leading "green" analytical and purification separations technology. Modern supercritical fluid chromatography (SFC) is the leading method used to analyze and purify chiral and achiral chemical compounds, many of which are pharmaceuticals, pharmaceutical candidates, and natural products including cannabis-related compounds. This book covers current SFC instrumentation as it relates to greater robustness, better reproducibility, and increased analytical sensitivity. Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases covers the history, instrumentation, method development and applications of SFC. The authors provided readers with an overview of analytical and preparative SFC equipment, stationary phases, and mobile phase choices. Topics covered include: Milestones of Supercritical Fluid Chromatography; Physical Properties of Supercritical Fluids; Instrumentation for SFC; Detection in SFC; Achiral SFC Method Development; Chiral SFC Method Development; and Preparative Scale SFC. The book also includes highlights of modern applications of SFC in the final chapters—namely pharmaceuticals, consumer products, foods, polymers, petroleum-related mixtures, and cannabis—and discusses the future of SFC. Provides a clear explanation of the physical and chemical properties of supercritical fluids, which gives the reader a better understanding of the basis for improved performance in SFC compared to HPLC and GC Describes the advantages of SFC as a green alternative to HPLC and GC for the analysis of both polar, water-soluble, and non-polar analytes Details both achiral and chiral SFC method development, including modifiers, additives, the impact of temperature and pressure, and stationary phase choices Details why SFC is the premier modern preparative chromatographic technique used to purify components of mixtures for subsequent uses, both from performance and economic perspectives Covers numerous detectors, with an emphasis on SFC-MS, SFC-UV, and SFC-ELSD (evaporative light scattering detection) Describes the application of SFC to numerous high-value application areas Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases will be of great interest to professionals, students, and professors involved in analytical, bioanalytical, separations science, medicinal, petroleum, and environmental chemistries. It will also appeal to pharmaceutical scientists, natural-product scientists, food and consumer-products scientists, chemical engineers, and managers in these areas.
Limits of Detection in Chemical Analysis
Limits of Detection in Chemical Analysis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Limits of Detection in Chemical Analysis write by Edward Voigtman. This book was released on 2017-02-15. Limits of Detection in Chemical Analysis available in PDF, EPUB and Kindle. Details methods for computing valid limits of detection. Clearly explains analytical detection limit theory, thereby mitigating incorrect detection limit concepts, methodologies and results Extensive use of computer simulations that are freely available to readers Curated short-list of important references for limits of detection Videos, screencasts, and animations are provided at an associated website, to enhance understanding Illustrated, with many detailed examples and cogent explanations
Practical High-Performance Liquid Chromatography
Practical High-Performance Liquid Chromatography - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Practical High-Performance Liquid Chromatography write by Veronika R. Meyer. This book was released on 2004-10. Practical High-Performance Liquid Chromatography available in PDF, EPUB and Kindle. Publisher Description
