Selectivity in Organic Synthesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Selectivity in Organic Synthesis write by Robert S. Ward. This book was released on 1999-05-04. Selectivity in Organic Synthesis available in PDF, EPUB and Kindle. Selectivity is an increasingly important part of organic synthesis. The whole basis of organic chemistry, and especially organic synthesis, depends upon the selectivity which can be achieved in organic reactions. This concise textbook describes the strategies which can be adopted to improve selectivity, and the reactions which have been specially designed to afford high selectivity. The aim is to illustrate the range of processes to which these principles can be applied and the high degree of selectivity which can be achieved. Selectivity in Organic Synthesis aims to provide a solid introduction to this subject, focusing on the key areas and applications.
Lewis Acids and Selectivity in Organic Synthesis
Lewis Acids and Selectivity in Organic Synthesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Lewis Acids and Selectivity in Organic Synthesis write by M. Santelli. This book was released on 1995-11-21. Lewis Acids and Selectivity in Organic Synthesis available in PDF, EPUB and Kindle. Lewis acids provide inexpensive access to elaborated molecules obtained with high selectivities (regio-, stereo-, and enantioselectivity). Lewis Acids and Selectivity in Organic Synthesis is the first book to deal with these new and promising roles of Lewis acids. The book begins with general considerations on Lewis acids and a description of Lewis acid-carbonyl complexes, which are involved in most of the reactions described: ene reactions, allylsilane and allyltin addition to carbonyl compounds, addition of nucleophiles to acetals, conjugated addition of allylsilanes and allyltins to unsaturated carbonyl compounds (Sakurai reaction), and Diels-Alder reaction. Subsequent chapters examine these issue in detail, with special attention given to the way Lewis acids induce diastereo- and enantioselectivity. The extensive use of schemes (approximately 1000) ensures rapid visual uptake of the information. Lewis Acids and Selectivity in Organic Synthesis serves as a valuable source of information for all who face the challenge of selectivity in organic synthesis.
Organolithiums: Selectivity for Synthesis
Organolithiums: Selectivity for Synthesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Organolithiums: Selectivity for Synthesis write by Jonathan Clayden. This book was released on 2002-07-12. Organolithiums: Selectivity for Synthesis available in PDF, EPUB and Kindle. This volume, number 23 in the "Tetrahedron Organic Chemistry" series, presents organolithium chemistry from the perspective of a synthetic organic chemist, drawing from the synthetic literature to present a unified overview of how organolithiums can be used to make molecules. The development of methods for the regioselective synthesis of organolithiums has replaced their image of indiscriminate high reactivity with one of controllable and subtle selectivity. Organolithium chemistry has a central role in the selective construction of C-C bonds in both simple and complex molecules, and for example has arguably overtaken aromatic electrophilic substitution as the most powerful method for regioselective functionalisation of aromatic rings. The twin themes of reactivity and selectivity run through the book, which reviews the ways by which organolithiums may be formed and the ways in which they react. Topics include advances in directed metallation, reductive lithiation and organolithium cyclisation reactions, along with a discussion of organolithium stereochemistry and the role played by ligands such as (-)-sparteine.
Comprehensive Organic Synthesis
Comprehensive Organic Synthesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Comprehensive Organic Synthesis write by Barry M. Trost. This book was released on 1991. Comprehensive Organic Synthesis available in PDF, EPUB and Kindle. Volume 8.
Organic Synthesis
Organic Synthesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Organic Synthesis write by Michael Smith. This book was released on 2016-11-22. Organic Synthesis available in PDF, EPUB and Kindle. Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. A full Solutions Manual is also available online for qualified instructors, to support teaching. Winner, 2018 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association Fully revised and updated throughout, and organized into 19 chapters for a more cogent and versatile presentation of concepts Includes reaction examples taken from literature research reported between 2010-2015 Features new full-color art and new chapter content on process chemistry and green organic chemistry Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Solutions Manual for qualified course instructors
