Signaling Through the Cell Matrix

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Release : 2012-12-06
Genre : Science
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Book Rating : 661/5 ( reviews)

Signaling Through the Cell Matrix - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Signaling Through the Cell Matrix write by Alvaro Macieira-Coelho. This book was released on 2012-12-06. Signaling Through the Cell Matrix available in PDF, EPUB and Kindle. This book covers a hot subject in cell biology; i.e. how the cell environment sends messages to the cell, regulates gene expression, and modulates the cell phenotype. For a long time the extracellular matrix was believed to have only a supporting role for cell attachement. However, it became apparent that the matrix participates actively in cell metabolism. The experiments that led to this conclusion are described in this volume. Progressively, molecules have been identified that transmit this signaling at the cell-matrix interface. Their identity and mechanism of action are also illustrated in this book. Finally, it explains the role the cell-matrix relationship plays in the regulation of cell proliferation, cell differentiation, and the expression of malignancy.

Molecular Biology of The Cell

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Release : 2002
Genre : Cytology
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Book Rating : 183/5 ( reviews)

Molecular Biology of The Cell - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Biology of The Cell write by Bruce Alberts. This book was released on 2002. Molecular Biology of The Cell available in PDF, EPUB and Kindle.

Cell-Extracellular Matrix Interactions in Cancer

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Release : 2010-01-23
Genre : Medical
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Book Rating : 145/5 ( reviews)

Cell-Extracellular Matrix Interactions in Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell-Extracellular Matrix Interactions in Cancer write by Roy Zent. This book was released on 2010-01-23. Cell-Extracellular Matrix Interactions in Cancer available in PDF, EPUB and Kindle. Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.

Cell-Extracellular Matrix Interactions in Cancer

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Release : 2010-10-22
Genre : Medical
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Book Rating : 153/5 ( reviews)

Cell-Extracellular Matrix Interactions in Cancer - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cell-Extracellular Matrix Interactions in Cancer write by Roy Zent. This book was released on 2010-10-22. Cell-Extracellular Matrix Interactions in Cancer available in PDF, EPUB and Kindle. Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.

The Extracellular Matrix: an Overview

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Release : 2011-02-16
Genre : Science
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Book Rating : 559/5 ( reviews)

The Extracellular Matrix: an Overview - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Extracellular Matrix: an Overview write by Robert Mecham. This book was released on 2011-02-16. The Extracellular Matrix: an Overview available in PDF, EPUB and Kindle. Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.