Smart External Stimulus- Responsive Nahb - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Smart External Stimulus- Responsive Nahb write by Mahdi Karimi. This book was released on 2024-06-15. Smart External Stimulus- Responsive Nahb available in PDF, EPUB and Kindle.
Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery
Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery write by Mahdi Karimi. This book was released on 2015-12-01. Smart External Stimulus-Responsive Nanocarriers for Drug and Gene Delivery available in PDF, EPUB and Kindle. The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally we discuss the issue of nanotoxicology and the future scope of the field.
Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery
Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery write by Mahdi Karimi. This book was released on 2015-12-01. Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery available in PDF, EPUB and Kindle. The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.
Biomedical Applications of Polymeric Materials and Composites
Biomedical Applications of Polymeric Materials and Composites - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Biomedical Applications of Polymeric Materials and Composites write by Raju Francis. This book was released on 2016-12-19. Biomedical Applications of Polymeric Materials and Composites available in PDF, EPUB and Kindle. With its content taken from only the very latest results, this is an extensive summary of the various polymeric materials used for biomedical applications. Following an introduction listing various functional polymers, including conductive, biocompatible and conjugated polymers, the book goes on to discuss different synthetic polymers that can be used, for example, as hydrogels, biochemical sensors, functional surfaces, and natural degradable materials. Throughout, the focus is on applications, with worked examples for training purposes as well as case studies included. The whole is rounded off with a look at future trends.
Nanopharmaceutical Advanced Delivery Systems
Nanopharmaceutical Advanced Delivery Systems - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Nanopharmaceutical Advanced Delivery Systems write by Vivek Dave. This book was released on 2020-12-29. Nanopharmaceutical Advanced Delivery Systems available in PDF, EPUB and Kindle. The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.
