Software-assisted Method Development In High Performance Liquid Chromatography

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Release : 2018-08-01
Genre : Science
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Book Rating : 471/5 ( reviews)

Software-assisted Method Development In High Performance Liquid Chromatography - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Software-assisted Method Development In High Performance Liquid Chromatography write by Szabolcs Fekete. This book was released on 2018-08-01. Software-assisted Method Development In High Performance Liquid Chromatography available in PDF, EPUB and Kindle. 'The book is a useful contribution in the field of HPLC, and may represent a valuable tool for chromatography practitioners in different fields, as well as teachers and instructors. The 12 chapters provide comprehensive insights of current day retention and resolution modelling in HPLC, and its applications for small and large molecule analysis. It may be a useful reference for specialists in pharmaceuticals but not limited to … It may be a valuable resource to assist scientists involved in method development, aiming to achieve the best results with reduced costs, time, and efforts.'Analytical and Bioanalytical ChemistryThis handbook gives a general overview of the possibilities in recent developments in chromatographic retention modeling. As a result of the latest developments in modeling software, several new features are now accessible, opening a new level in HPLC method development.Many of these current possibilities in software assisted liquid chromatographic method modeling for analytical purposes are presented. Several modes of chromatography, including Reversed-Phase Liquid Chromatography (RPLC), Ion Exchange Chromatography (IEX), Hydrophobic Interaction Chromatography (HIC), and Hydrophilic Interaction Liquid Chromatography (HILIC) are explained in detail. For all these chromatographic modes, the most important variables for tuning retention and selectivity are exposed.Beside the industrial and practical benefits of retention modeling, the possibilities in teaching and education are also illustrated. Finally, numerous representative industrial examples are shown, to highlight the benefits, time and cost savings offered by state-of-the-art software assisted HPLC method development.

Computer-assisted Method Development for High-performance Liquid Chromatography

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Release : 1990
Genre : Science
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Book Rating : /5 ( reviews)

Computer-assisted Method Development for High-performance Liquid Chromatography - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Computer-assisted Method Development for High-performance Liquid Chromatography write by Joseph L. Glajch. This book was released on 1990. Computer-assisted Method Development for High-performance Liquid Chromatography available in PDF, EPUB and Kindle. This book deals with the use of the computer as an aid in selecting adequate or optimum conditions for a given analytical separation. Originally published as Volume 485 of the Journal of Chromatography, it has now been reprinted in book form, since the information is so useful that many chromatographers want a copy readily available in the lab. An extensive Introduction is added to the book edition. This surveys the field and refers to the pages where particular items are discussed in the book. The addition of a Glossary of Terms, an Author Index and a Subject Index make this book an invaluable source of easily consulted information for the practising chromatographer. For the purpose of this book, computer-assisted method development will be limited to specific procedures which are intended to be used with a computer - rather than their manually applied precursors. In that sense, the subject can be considered to have begun around 1980. The ongoing, intense research activity into various forms of computer assisted HPLC method development provides the assurance that this approach can really assist the practical chromatographer working in an industrial laboratory.

Analytical Method Development and Validation

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Release : 2018-10-03
Genre : Science
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Book Rating : 773/5 ( reviews)

Analytical Method Development and Validation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Analytical Method Development and Validation write by Michael E. Swartz. This book was released on 2018-10-03. Analytical Method Development and Validation available in PDF, EPUB and Kindle. Describes analytical methods development, optimization and validation, and provides examples of successful methods development and validation in high-performance liquid chromatography (HPLC) areas. The text presents an overview of Food and Drug Administration (FDA)/International Conference on Harmonization (ICH) regulatory guidelines, compliance with validation requirements for regulatory agencies, and methods validation criteria stipulated by the US Pharmacopia, FDA and ICH.

Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations: HPLC And HPTLC Techniques

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Release : 2015-08-01
Genre : Science
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Book Rating : 071/5 ( reviews)

Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations: HPLC And HPTLC Techniques - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations: HPLC And HPTLC Techniques write by Satish Y. Gabhe. This book was released on 2015-08-01. Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations: HPLC And HPTLC Techniques available in PDF, EPUB and Kindle. This book details: 1. Development and validation of a HPTLC-densitometric method for concurrent estimation of metformin hydrochloride, pioglitazone hydrochloride and gliclazide in combined dosage form. 2. Development and validation of a HPTLC method for simultaneous estimation of moxifloxacin hydrochloride and dexamethasone sodium phosphate in combined pharmaceutical dosage form. 3. Development and validation of a RP-HPLC method for simultaneous estimation of ciprofloxacin hydrochloride and dexamethasone in combined dosage form, which is a better alternative to existing ones. The developed analytical methods are simple, selective, accurate, robust, and precise with shorter analysis time for the analysis of drug/s in combined pharmaceutical dosage forms. All the developed HPTLC and HPLC methods have been validated as per ICH Q2 (R1) guideline. Developed analytical methods could boost analytical researchers to work more efficiently in the field of analytical method development and validation of Pharmaceutical dosage forms.

Practical HPLC Method Development

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Release : 2012-12-03
Genre : Science
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Book Rating : 518/5 ( reviews)

Practical HPLC Method Development - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Practical HPLC Method Development write by Lloyd R. Snyder. This book was released on 2012-12-03. Practical HPLC Method Development available in PDF, EPUB and Kindle. This revision brings the reader completely up to date on the evolving methods associated with increasingly more complex sample types analyzed using high-performance liquid chromatography, or HPLC. The book also incorporates updated discussions of many of the fundamental components of HPLC systems and practical issues associated with the use of this analytical method. This edition includes new or expanded treatments of sample preparation, computer assisted method development, as well as biochemical samples, and chiral separations.