Solid State Characterization of Pharmaceuticals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Solid State Characterization of Pharmaceuticals write by Richard A. Storey. This book was released on 2011-03-31. Solid State Characterization of Pharmaceuticals available in PDF, EPUB and Kindle. The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanced, practical coverage with industrial relevance, it covers a range of key applications in the field. The following topics are included: Physical properties and processes Thermodynamics Intellectual guidance X-ray diffraction Spectroscopy Microscopy Particle sizing Mechanical properties Vapour sorption Thermal analysis & Calorimetry Polymorph prediction Form selection
Solid State Characterization of Pharmaceuticals
Solid State Characterization of Pharmaceuticals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Solid State Characterization of Pharmaceuticals write by Angeline Zakrzewski. This book was released on 2006. Solid State Characterization of Pharmaceuticals available in PDF, EPUB and Kindle.
Solid-State Properties of Pharmaceutical Materials
Solid-State Properties of Pharmaceutical Materials - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Solid-State Properties of Pharmaceutical Materials write by Stephen R. Byrn. This book was released on 2017-08-28. Solid-State Properties of Pharmaceutical Materials available in PDF, EPUB and Kindle. Presents a detailed discussion of important solid-state properties, methods, and applications of solid-state analysis Illustrates the various phases or forms that solids can assume and discussesvarious issues related to the relative stability of solid forms and tendencies to undergo transformation Covers key methods of solid state analysis including X-ray powder diffraction, thermal analysis, microscopy, spectroscopy, and solid state NMR Reviews critical physical attributes of pharmaceutical materials, mainly related to drug substances, including particle size/surface area, hygroscopicity, mechanical properties, solubility, and physical and chemical stability Showcases the application of solid state material science in rational selection of drug solid forms, analysis of various solid forms within drug substance and the drug product, and pharmaceutical product development Introduces appropriate manufacturing and control procedures using Quality by Design, and other strategies that lead to safe and effective products with a minimum of resources and time
Solid State Development and Processing of Pharmaceutical Molecules
Solid State Development and Processing of Pharmaceutical Molecules - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Solid State Development and Processing of Pharmaceutical Molecules write by Michael Gruss. This book was released on 2021-11-15. Solid State Development and Processing of Pharmaceutical Molecules available in PDF, EPUB and Kindle. Solid State Development and Processing of Pharmaceutical Molecules A guide to the lastest industry principles for optimizing the production of solid state active pharmaceutical ingredients Solid State Development and Processing of Pharmaceutical Molecules is an authoritative guide that covers the entire pharmaceutical value chain. The authors—noted experts on the topic—examine the importance of the solid state form of chemical and biological drugs and review the development, production, quality control, formulation, and stability of medicines. The book explores the most recent trends in the digitization and automation of the pharmaceutical production processes that reflect the need for consistent high quality. It also includes information on relevant regulatory and intellectual property considerations. This resource is aimed at professionals in the pharmaceutical industry and offers an in-depth examination of the commercially relevant issues facing developers, producers and distributors of drug substances. This important book: Provides a guide for the effective development of solid drug forms Compares different characterization methods for solid state APIs Offers a resource for understanding efficient production methods for solid state forms of chemical and biological drugs Includes information on automation, process control, and machine learning as an integral part of the development and production workflows Covers in detail the regulatory and quality control aspects of drug development Written for medicinal chemists, pharmaceutical industry professionals, pharma engineers, solid state chemists, chemical engineers, Solid State Development and Processing of Pharmaceutical Molecules reviews information on the solid state of active pharmaceutical ingredients for their efficient development and production.
Developing Solid Oral Dosage Forms
Developing Solid Oral Dosage Forms - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Developing Solid Oral Dosage Forms write by Yihong Qiu. This book was released on 2009-03-10. Developing Solid Oral Dosage Forms available in PDF, EPUB and Kindle. Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies
