Special Issue on Structured Prediction - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Special Issue on Structured Prediction write by Charles Parker. This book was released on 2009. Special Issue on Structured Prediction available in PDF, EPUB and Kindle.
Protein Structure Prediction
Protein Structure Prediction - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Structure Prediction write by David Webster. This book was released on 2008-02-03. Protein Structure Prediction available in PDF, EPUB and Kindle. The number of protein sequences grows each year, yet the number of structures deposited in the Protein Data Bank remains relatively small. The importance of protein structure prediction cannot be overemphasized, and this volume is a timely addition to the literature in this field. Protein Structure Prediction: Methods and Protocols is a departure from the normal Methods in Molecular Biology series format. By its very nature, protein structure prediction demands that there be a greater mix of theoretical and practical aspects than is normally seen in this series. This book is aimed at both the novice and the experienced researcher who wish for detailed inf- mation in the field of protein structure prediction; a major intention here is to include important information that is needed in the day-to-day work of a research scientist, important information that is not always decipherable in scientific literature. Protein Structure Prediction: Methods and Protocols covers the topic of protein structure prediction in an eclectic fashion, detailing aspects of pred- tion that range from sequence analysis (a starting point for many algorithms) to secondary and tertiary methods, on into the prediction of docked complexes (an essential point in order to fully understand biological function). As this volume progresses, the authors contribute their expert knowledge of protein structure prediction to many disciplines, such as the identification of motifs and domains, the comparative modeling of proteins, and ab initio approaches to protein loop, side chain, and protein prediction.
Introduction to Protein Structure Prediction
Introduction to Protein Structure Prediction - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Introduction to Protein Structure Prediction write by Huzefa Rangwala. This book was released on 2011-03-16. Introduction to Protein Structure Prediction available in PDF, EPUB and Kindle. A look at the methods and algorithms used to predict protein structure A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered: Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutant Whether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.
Advanced Structured Prediction
Advanced Structured Prediction - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Advanced Structured Prediction write by Sebastian Nowozin. This book was released on 2014-11-21. Advanced Structured Prediction available in PDF, EPUB and Kindle. An overview of recent work in the field of structured prediction, the building of predictive machine learning models for interrelated and dependent outputs. The goal of structured prediction is to build machine learning models that predict relational information that itself has structure, such as being composed of multiple interrelated parts. These models, which reflect prior knowledge, task-specific relations, and constraints, are used in fields including computer vision, speech recognition, natural language processing, and computational biology. They can carry out such tasks as predicting a natural language sentence, or segmenting an image into meaningful components. These models are expressive and powerful, but exact computation is often intractable. A broad research effort in recent years has aimed at designing structured prediction models and approximate inference and learning procedures that are computationally efficient. This volume offers an overview of this recent research in order to make the work accessible to a broader research community. The chapters, by leading researchers in the field, cover a range of topics, including research trends, the linear programming relaxation approach, innovations in probabilistic modeling, recent theoretical progress, and resource-aware learning. Contributors Jonas Behr, Yutian Chen, Fernando De La Torre, Justin Domke, Peter V. Gehler, Andrew E. Gelfand, Sébastien Giguère, Amir Globerson, Fred A. Hamprecht, Minh Hoai, Tommi Jaakkola, Jeremy Jancsary, Joseph Keshet, Marius Kloft, Vladimir Kolmogorov, Christoph H. Lampert, François Laviolette, Xinghua Lou, Mario Marchand, André F. T. Martins, Ofer Meshi, Sebastian Nowozin, George Papandreou, Daniel Průša, Gunnar Rätsch, Amélie Rolland, Bogdan Savchynskyy, Stefan Schmidt, Thomas Schoenemann, Gabriele Schweikert, Ben Taskar, Sinisa Todorovic, Max Welling, David Weiss, Thomáš Werner, Alan Yuille, Stanislav Živný
Protein Structure Prediction
Protein Structure Prediction - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Structure Prediction write by Mohammed Zaki. This book was released on 2007-09-12. Protein Structure Prediction available in PDF, EPUB and Kindle. This book covers elements of both the data-driven comparative modeling approach to structure prediction and also recent attempts to simulate folding using explicit or simplified models. Despite the unsolved mystery of how a protein folds, advances are being made in predicting the interactions of proteins with other molecules. Also rapidly advancing are the methods for solving the inverse folding problem, the problem of finding a sequence to fit a structure. This book focuses on the various computational methods for prediction, their successes and their limitations, from the perspective of their most well known practitioners.
