Stereoselective Synthesis of Drugs and Natural Products

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Release : 2013-08-16
Genre : Science
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Book Rating : 330/5 ( reviews)

Stereoselective Synthesis of Drugs and Natural Products - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Stereoselective Synthesis of Drugs and Natural Products write by Vasyl Andrushko. This book was released on 2013-08-16. Stereoselective Synthesis of Drugs and Natural Products available in PDF, EPUB and Kindle. Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Total Synthesis of Natural Products

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Release : 2013-03-14
Genre : Science
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Book Rating : 652/5 ( reviews)

Total Synthesis of Natural Products - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Total Synthesis of Natural Products write by Jie Jack Li. This book was released on 2013-03-14. Total Synthesis of Natural Products available in PDF, EPUB and Kindle. 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Fundamentals of Asymmetric Catalysis

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Release : 2009-01-02
Genre : Science
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Book Rating : 542/5 ( reviews)

Fundamentals of Asymmetric Catalysis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Fundamentals of Asymmetric Catalysis write by Patrick J. Walsh. This book was released on 2009-01-02. Fundamentals of Asymmetric Catalysis available in PDF, EPUB and Kindle. This work describes the essential aspects of enantioselective catalysis, with chapters organised by concept rather than by reaction type. Each concept is supported by examples to give the reader broad exposure to a wide range of catalysts, reactions and reaction mechanisms.

Organic Syntheses Based on Name Reactions and Unnamed Reactions

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Release : 2013-10-22
Genre : Science
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Book Rating : 343/5 ( reviews)

Organic Syntheses Based on Name Reactions and Unnamed Reactions - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Organic Syntheses Based on Name Reactions and Unnamed Reactions write by Alfred Hassner. This book was released on 2013-10-22. Organic Syntheses Based on Name Reactions and Unnamed Reactions available in PDF, EPUB and Kindle. Synthetically useful organic reactions or reagents are often referred to by the name of the discoverer(s) or developer(s). Older name reactions are described in text books, but more recently developed synthetically useful reactions that may have been associated occasionally with a name are not always well known. For neither of the above are experimental procedures or references easy to find. In this monograph approximately 500 name reactions are included, of which over 200 represent newer name reactions and modern reagents. Each of these reactions are extremely useful for the contemporary organic chemistry researcher in industry or academic institutions. This book provides the information in an easily accessible form. In addition to seminal references and reviews, one or more examples for each name reaction are provided and a complete typical experimental procedure is included, to enable the student or researcher to immediately evaluate reaction conditions. Besides an alphabetical listing of reactions and reagents, cross references permit the organic practitioner to find those name reactions or reagents that enable specific transformations, such as, conversion of amines to nitriles, stereoselective reduction, fluoroalkylation, phenol alkynylation, asymmetric syntheses, allylic alkylation, nucleoside synthesis, cyclopentanation, hydrozirconation, to name a few. Emphasis has been placed on stereoselective and regioselective transformations as well as on enantioselective processes. The listing of reactions and reagents is supported by four indexes.

Natural Products as Source of Molecules with Therapeutic Potential

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Release : 2018-12-07
Genre : Science
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Book Rating : 453/5 ( reviews)

Natural Products as Source of Molecules with Therapeutic Potential - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Natural Products as Source of Molecules with Therapeutic Potential write by Valdir Cechinel Filho. This book was released on 2018-12-07. Natural Products as Source of Molecules with Therapeutic Potential available in PDF, EPUB and Kindle. This book addresses the highly relevant and complex subject of research on drugs from natural products, discussing the current hot topics in the field. It also provides a detailed overview of the strategies used to research and develop these drugs. Respected experts explore issues involved in the production chain and when looking for new medicinal agents, including aspects such as therapeutic potential, functional foods, ethnopharmacology, metabolomics, virtual screening and regulatory scenarios. Further, the book describes strategic methods of isolation and characterization of active principles, biological assays, biotechnology of plants, synthesis, clinical trials and the use of tools to identity active principles.