Structure, Function, and Modulation of Neuronal Voltage-Gated Ion Channels - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Structure, Function, and Modulation of Neuronal Voltage-Gated Ion Channels write by Valentin K. Gribkoff. This book was released on 2008-12-09. Structure, Function, and Modulation of Neuronal Voltage-Gated Ion Channels available in PDF, EPUB and Kindle. This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important reference for research scientists and drug discovery companies.
Voltage Gated Sodium Channels
Voltage Gated Sodium Channels - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Voltage Gated Sodium Channels write by Peter C. Ruben. This book was released on 2014-04-15. Voltage Gated Sodium Channels available in PDF, EPUB and Kindle. A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.
Ion Channels
Ion Channels - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ion Channels write by James N. C. Kew. This book was released on 2010. Ion Channels available in PDF, EPUB and Kindle. Ion channels are intimately involved in the everyday physiological functions that enable us to live a full and varied life. When disease strikes, malfunction of ion channels or their dependent is often involved, either as the cause or the effect of the illness. Thus, billions of dollars have been, and still are being, invested in research to understand the physiological and pathophysiological functions of ion channels in an attempt to develop novel therapeutic treatments for a wide range of diseases. This book provides a comprehensive overview of ion channel structure and function. It comprises two major parts. Part one is an introductory overview of the ion channel superfamily and the generic aspects of ion channel function. This part also reviews the methodologies by which ion channel function can be studied from the perspective of performing detailed biophysical characterization through to the deployment of high throughput approaches for identifying novel ion channel ligands. Part two of the book provides an in-depth review of the individual ion channel subfamilies and, as such, is subdivided into four broad sections: Voltage-Gated Ion Channels, Extracellular Ligand-Gated Ion Channels, Intracellular Ligand-Gated Ion Channels, and Polymodal-Gated Ion Channels, with each chapter focused on specific family members. These chapters have been written by world leading experts and provide a detailed overview of the structure, biophysics, localization, pharmacology, physiology, and disease relevance of each particular ion channel subfamily. Reviewing both the basic principles of ion channel function and providing a detailed up-to-date review of the phsyiological and pharmacological aspects of individual ion channel sub-families, this book constitutes both an excellent introduction to the field for non-specialists, as well as a highly valuable reference text for experienced researchers already working in the ion channel area.
Molecular Biology of The Cell
Molecular Biology of The Cell - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Biology of The Cell write by Bruce Alberts. This book was released on 2002. Molecular Biology of The Cell available in PDF, EPUB and Kindle.
An Optical Approach to Structure-function Relationships in Voltage-gated Ion Channels
An Optical Approach to Structure-function Relationships in Voltage-gated Ion Channels - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook An Optical Approach to Structure-function Relationships in Voltage-gated Ion Channels write by Osei Kwame Asamoah. This book was released on 2004. An Optical Approach to Structure-function Relationships in Voltage-gated Ion Channels available in PDF, EPUB and Kindle.
