Studies on the Evolution, Structure, and Function of Homing Endonuclease Containing Parasitic Genetic Elements

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Release : 2007
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Studies on the Evolution, Structure, and Function of Homing Endonuclease Containing Parasitic Genetic Elements - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Studies on the Evolution, Structure, and Function of Homing Endonuclease Containing Parasitic Genetic Elements write by Alireza Ghodsi Senejani. This book was released on 2007. Studies on the Evolution, Structure, and Function of Homing Endonuclease Containing Parasitic Genetic Elements available in PDF, EPUB and Kindle.

Gene Drives on the Horizon

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Release : 2016-08-28
Genre : Science
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Book Rating : 873/5 ( reviews)

Gene Drives on the Horizon - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Gene Drives on the Horizon write by National Academies of Sciences, Engineering, and Medicine. This book was released on 2016-08-28. Gene Drives on the Horizon available in PDF, EPUB and Kindle. Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.

Dissertation Abstracts International

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Release : 2008
Genre : Dissertations, Academic
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Dissertation Abstracts International - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Dissertation Abstracts International write by . This book was released on 2008. Dissertation Abstracts International available in PDF, EPUB and Kindle.

Homing Endonucleases and Inteins

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Release : 2008-09-22
Genre : Science
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Book Rating : 353/5 ( reviews)

Homing Endonucleases and Inteins - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Homing Endonucleases and Inteins write by Marlene Belfort. This book was released on 2008-09-22. Homing Endonucleases and Inteins available in PDF, EPUB and Kindle. This book provides the first and only comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies, which are tied together through their frequent fusion and coevolution, have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations.

Restriction Endonucleases

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Release : 2012-12-06
Genre : Science
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Book Rating : 516/5 ( reviews)

Restriction Endonucleases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Restriction Endonucleases write by Alfred Pingoud. This book was released on 2012-12-06. Restriction Endonucleases available in PDF, EPUB and Kindle. Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.