Modern Supercritical Fluid Chromatography

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Release : 2019-12-12
Genre : Science
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Book Rating : 394/5 ( reviews)

Modern Supercritical Fluid Chromatography - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Modern Supercritical Fluid Chromatography write by Larry M. Miller. This book was released on 2019-12-12. Modern Supercritical Fluid Chromatography available in PDF, EPUB and Kindle. Explains why modern supercritical fluid chromatography (SFC) is the leading "green" analytical and purification separations technology. Modern supercritical fluid chromatography (SFC) is the leading method used to analyze and purify chiral and achiral chemical compounds, many of which are pharmaceuticals, pharmaceutical candidates, and natural products including cannabis-related compounds. This book covers current SFC instrumentation as it relates to greater robustness, better reproducibility, and increased analytical sensitivity. Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases covers the history, instrumentation, method development and applications of SFC. The authors provided readers with an overview of analytical and preparative SFC equipment, stationary phases, and mobile phase choices. Topics covered include: Milestones of Supercritical Fluid Chromatography; Physical Properties of Supercritical Fluids; Instrumentation for SFC; Detection in SFC; Achiral SFC Method Development; Chiral SFC Method Development; and Preparative Scale SFC. The book also includes highlights of modern applications of SFC in the final chapters—namely pharmaceuticals, consumer products, foods, polymers, petroleum-related mixtures, and cannabis—and discusses the future of SFC. Provides a clear explanation of the physical and chemical properties of supercritical fluids, which gives the reader a better understanding of the basis for improved performance in SFC compared to HPLC and GC Describes the advantages of SFC as a green alternative to HPLC and GC for the analysis of both polar, water-soluble, and non-polar analytes Details both achiral and chiral SFC method development, including modifiers, additives, the impact of temperature and pressure, and stationary phase choices Details why SFC is the premier modern preparative chromatographic technique used to purify components of mixtures for subsequent uses, both from performance and economic perspectives Covers numerous detectors, with an emphasis on SFC-MS, SFC-UV, and SFC-ELSD (evaporative light scattering detection) Describes the application of SFC to numerous high-value application areas Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases will be of great interest to professionals, students, and professors involved in analytical, bioanalytical, separations science, medicinal, petroleum, and environmental chemistries. It will also appeal to pharmaceutical scientists, natural-product scientists, food and consumer-products scientists, chemical engineers, and managers in these areas.

Supercritical Fluid Chromatography

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Release : 2017-02-16
Genre : Science
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Book Rating : 676/5 ( reviews)

Supercritical Fluid Chromatography - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Supercritical Fluid Chromatography write by Colin F. Poole. This book was released on 2017-02-16. Supercritical Fluid Chromatography available in PDF, EPUB and Kindle. Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Significant improvements in instrumentation have rekindled interest in SFC in recent years and enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its strengths and weaknesses, but the possibilities brought to the table by SFC are less well-known and are underappreciated. Supercritical Fluid Chromatography is a thorough and encompassing reference that defines the concept of contemporary practice in SFC and how it should be implemented in laboratory science. Given the changes that have taken place in SFC, this book presents contemporary aspects and applications of the technique and introduces SFC as a natural solution in the larger field of separation science. The focus on state-of-the-art instrumental SFC distinguishes this work as the go-to reference work for those interested in implementing the technique at an advanced level. Edited and authored by world-leading chromatography experts Provides comprehensive coverage of SFC in a single source Extensive referencing facilitates identification of key research developments More than 200 figures and tables aid in the retention of key concepts

Supercritical Fluid Chromatography

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Release : 2018-12-17
Genre : Science
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Book Rating : 779/5 ( reviews)

Supercritical Fluid Chromatography - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Supercritical Fluid Chromatography write by Gérard Rossé. This book was released on 2018-12-17. Supercritical Fluid Chromatography available in PDF, EPUB and Kindle. Supercritical Fluid Chromatography (SFC) provides a timely overview of SFC application areas which were unimaginable just a decade ago. This two-volume series opens with an overview of the history and expectant future of SFC and continues with recent applications in the pharmaceutical industry and other fascinating areas of science. SFC has found its place in the pharmaceutical industry with an increasing body of applications for chiral and achiral molecules in both the research and development phases of the drug discovery process. As illustrated in this two-volume series, the current interest in SFC extends well beyond the pharmaceutical industry. Chapters encompassing applications for polar and non-polar mixtures of importance are covering widely disparate areas in substance abuse, natural products including cannabinoids, bioactive lipids, flavor and fragrance. With its broad balance and coverage, this two-volume book constitutes a unique educational platform to students and scientists for many years to come. The major objective of this book editions is to inspire and stimulate readers to continue exploring the possibilities of exploiting supercritical fluids as a particular media for analysis, purifications and synthesis

Packed Column SFC

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Release : 2007-10-31
Genre : Science
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Book Rating : 602/5 ( reviews)

Packed Column SFC - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Packed Column SFC write by T A Berger. This book was released on 2007-10-31. Packed Column SFC available in PDF, EPUB and Kindle. Packed Column SFC is the third title to be published in this series and has been produced as a result of the dramatic re-emergence, in the last three years, of packed column instrumentation. This has led to a redefinition of the technique and an urgent need for a practical guide that deals with its subtleties. This book fulfils that need and deals exclusively with packed column SFC. It places the emphasis on understanding the underlying chemistry in order to perform rapid, systematic optimizations and provides many practical tips to help the new user avoid problems unique to SFC. It also proposes a detailed scheme for method development and provides lists of prioritized guidelines. The book clears up some of the confusion that surrounds the analytical use of supercritical fluids and assists the user in understanding the power and utility of this technique. Detailed chapters cover the most promising new application areas for packed column SFC, which are often overlooked in the mainstream chromatography literature. Like the other books in this popular series, Packed Column SFC will prove an invaluable guide and is essential reading for graduates, postgraduates and researchers with interests in pharmaceuticals, agricultural chemistry, small polar drug molecules, chiral analysis, environmental chemistry, and chromatography/instrumentation.

Supercritical Fluid Chromatography

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Release : 2014-02-04
Genre : Medical
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Book Rating : 019/5 ( reviews)

Supercritical Fluid Chromatography - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Supercritical Fluid Chromatography write by Gregory K. Webster. This book was released on 2014-02-04. Supercritical Fluid Chromatography available in PDF, EPUB and Kindle. Analytical chemists in the pharmaceutical industry are always looking for more-efficient techniques to meet the analytical challenges of today's pharmaceutical industry. One technique that has made steady advances in pharmaceutical analysis is supercritical fluid chromatography (SFC). SFC is meeting the chromatography needs of the industry by provi