Synthetic Receptors for Biomolecules - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Synthetic Receptors for Biomolecules write by Bradley D. Smith. This book was released on 2015-07-10. Synthetic Receptors for Biomolecules available in PDF, EPUB and Kindle. Synthetic receptor molecules, molecules that mimic antibody recognition, are widely used for developing drug leads; drug delivery vehicles; imaging agents; sensing agents; capture agents and separation systems. Synthetic Receptors for Biomolecules covers the most effective synthetic receptors for each major class of biomolecules within the context of specific applications. The book starts with an introduction to the applications of synthetic receptors for biomolecules and their design and synthesis for biomolecule recognition. Dedicated chapters then cover synthetic receptors for the key biomolecules including inorganic cations; small organic and inorganic anions; carbohydrates; nucleosides/nucleotides; oligonucleotides; amino acids and peptides; protein surfaces as well as non-polar and polar lipids; Each chapter follows the same systematic format of (a) chemical structures and physical properties of the biomolecule, (b) biological recognition of the biomolecule, (c) synthetic receptors for the biomolecule, (d) future directions and challenges. Edited by a leader in the field, the book is written in an accessible style for readers new to supramolecular chemistry or for those looking for synthetic receptors.
Functional Synthetic Receptors
Functional Synthetic Receptors - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Functional Synthetic Receptors write by Thomas Schrader. This book was released on 2006-03-06. Functional Synthetic Receptors available in PDF, EPUB and Kindle. A timely overview of this rapidly-expanding topic, covering the most important classes of compounds and incorporating the latest literature. With its application-oriented approach, this book is the first to emphasize current and potential applications, extending to such fields as materials science, bioorganic chemistry, medicinal chemistry, and organic synthesis. In the biological context in particular, the book clarifies which receptor systems work well in water or better under physiological conditions. From the contents: * Amino Acid, Peptid and Protein Receptors * Carbohydrate Receptors * Ammonium, Amidinium and Guanidinium Receptors * Anion Receptors * Molecular Capsules and Self Assembly * Dynamic Combinatorial Libraries based on Molecular Recognition * Molecular Machines * Self-Replication Aimed at graduate students and specialists in the field, this is also of interest to pharmaceutical companies involved in drug design, as well as chemical companies with a polymer or nanotechnology group. In addition, analytical companies working on the advanced equipment covered here will find stimulating new applications.
Designing Receptors for the Next Generation of Biosensors
Designing Receptors for the Next Generation of Biosensors - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Designing Receptors for the Next Generation of Biosensors write by Sergey A. Piletsky. This book was released on 2012-09-26. Designing Receptors for the Next Generation of Biosensors available in PDF, EPUB and Kindle. Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the detection of pathogenic microorganisms, the development of molecularly imprinted polymer (MIP) nanoparticles, the in silico design of MIPs and MIP-based sensors, and two chapters examining the development of sensors from an industrial point of view. The particular focus of all chapters is on practical aspects, either in the development process or the applications of the synthesized materials. This book will serve as an important reference work for business leaders and technology experts in the sensors and diagnostics sector.
Fluorescent Receptors for Biomolecules
Fluorescent Receptors for Biomolecules - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Fluorescent Receptors for Biomolecules write by Chi-Linh Do-Thanh. This book was released on 2011. Fluorescent Receptors for Biomolecules available in PDF, EPUB and Kindle. The development of synthetic receptors capable of high-affinity complexation of biologically relevant analytes in competitive solvent systems represents an ongoing challenge in molecular recognition. Anion recognition is particularly problematic, which is significant since numerous biological processes are regulated by anions, such as those resulting from phosphorylation. In this dissertation, we present the design and synthesis of a fluorescent sensor containing two cyclen groups that are preorganized to form a binding cleft for anion complexation. The receptor design includes a rigid acridine backbone, which is also exploited for fluorescence signal transduction. Furthermore, click chemistry is employed to facilitate receptor synthesis, and binding studies with various phosphorylated guest molecules are described. Additionally, the development of boronic acid-based carbohydrate receptors is presented. Carbohydrates play important roles in a large number of biochemical processes such as signal transduction and cell surface recognition events. The receptors will be used to study carbohydrate binding through Förster resonance energy transfer (FRET) and surface enhanced Raman spectroscopy (SERS). Another project involves the synthesis of aromatic compounds that can act as auxin herbicides. Auxins are plant hormones that play a major role in the regulation of plant growth and development. A modular synthetic strategy is employed to access a library of small molecules that will be tested for herbicidal activity on a variety of weeds. Finally, the work on the design and synthesis of molecular building blocks to generate covalently-bonded ordered organic frameworks is discussed.
Cellular and Biomolecular Recognition
Cellular and Biomolecular Recognition - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cellular and Biomolecular Recognition write by Raz Jelinek. This book was released on 2009-07-10. Cellular and Biomolecular Recognition available in PDF, EPUB and Kindle. With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology and medicine. The authors introduce innovative biomimetic chemical assemblies which constitute platforms for recruitment of cellular components or biological molecules, while also focusing on physical, chemical, and biological aspects of biomolecular recognition. The diverse applications covered include biosensors, cell adhesion, synthetic receptors, cell patterning, bioactive nanoparticles, and drug design.
