Systems Biology of Apoptosis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Systems Biology of Apoptosis write by Inna N. Lavrik. This book was released on 2012-09-13. Systems Biology of Apoptosis available in PDF, EPUB and Kindle. Systems Biology of Apoptosis summarizes all current achievements in this emerging field. Apoptosis is a process common to all multicellular organisms. Apoptosis leads to the elimination of cells via a complex but highly defined cellular programme. Defects in the regulation of apoptosis result in serious diseases such as cancer, autoimmunity, AIDS and neurodegeneration. Recently, a substantial step forward in understanding the complex apoptotic pathways has been made by utilising systems biology approaches. Systems biology combines rigorous mathematical modelling with experimental approaches in a closed loop cycle for advancing our knowledge about complex biological processes. In this book, the editor describes the contemporary systems biology studies devoted to apoptotic signaling and focuses on the question how systems biology helps to understand life/death decisions made in the cell and to develop new approaches to rational treatment strategies.
Computational Systems Biology
Computational Systems Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Computational Systems Biology write by Stefan M. Kallenberger. This book was released on 2013-11-26. Computational Systems Biology available in PDF, EPUB and Kindle. Apoptosis is a form of cellular suicide central to various aspects in biology including tissue homeostasis and embryonic development. It is typically dysregulated in cancer. Understanding the apoptotic signal transduction network is thus a central goal of cancer research. Quantitative modeling approaches provided valuable insights into determinants of cell fate decisions, and promise to become a valuable tool to optimize therapeutic strategies. In this chapter, we summarize modeling approaches used in systems biology of apoptosis. In addition, we give an overview of apoptosis-related research questions that can be addressed by modeling. Moreover, we review top-down and bottom-up modeling approaches applied to apoptosis, and particularly focus on ordinary differential equation (ODE) modeling. We describe bistability, temporal switching, crosstalk between death and survival, and discuss approaches to model cell-to-cell variability.
Essentials of Apoptosis
Essentials of Apoptosis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Essentials of Apoptosis write by Xiao-Ming Yin. This book was released on 2009-06-04. Essentials of Apoptosis available in PDF, EPUB and Kindle. This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.
Essentials of Apoptosis
Essentials of Apoptosis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Essentials of Apoptosis write by Xiao-Ming Yin. This book was released on 2016-05-01. Essentials of Apoptosis available in PDF, EPUB and Kindle. This is the second edition of the comprehensive, concise summary of apoptosis research, a topic that has grown fast in recent years. It covers the major concepts, molecular architecture, biochemical pathways, and pathophysiological significance of apoptosis.
Molecular Biology of The Cell
Molecular Biology of The Cell - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Biology of The Cell write by Bruce Alberts. This book was released on 2002. Molecular Biology of The Cell available in PDF, EPUB and Kindle.
