Systems Biology of Cell Signaling

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Release : 2021-09-28
Genre : Science
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Book Rating : 731/5 ( reviews)

Systems Biology of Cell Signaling - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Systems Biology of Cell Signaling write by James Ferrell. This book was released on 2021-09-28. Systems Biology of Cell Signaling available in PDF, EPUB and Kindle. How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes. Key Features: Full-color illustration program with diagrams to help illuminate the concepts Enables the reader to apply modeling and theory to the biological processes Further Reading for each chapter High-quality figures available for instructors to download

Systems Biology of Cell Signaling

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Release : 2022-02-17
Genre : Science
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Book Rating : 814/5 ( reviews)

Systems Biology of Cell Signaling - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Systems Biology of Cell Signaling write by Zhike Zi. This book was released on 2022-02-17. Systems Biology of Cell Signaling available in PDF, EPUB and Kindle. Topic Editor Prof. Xing is in collaboration with ATCC (https://www.atcc.org/) on testing some of their cell lines in research. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Systems Biology for Signaling Networks

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Release : 2010-08-09
Genre : Science
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Book Rating : 979/5 ( reviews)

Systems Biology for Signaling Networks - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Systems Biology for Signaling Networks write by Sangdun Choi. This book was released on 2010-08-09. Systems Biology for Signaling Networks available in PDF, EPUB and Kindle. System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc. not only to address key questions that are not answerable by individual fields alone, but also to help in our understanding of the complexities of biological systems. Whole genome expression studies have provided us the means of studying the expression of thousands of genes under a particular condition and this technique had been widely used to find out the role of key macromolecules that are involved in biological signaling pathways. However, making sense of the underlying complexity is only possible if we interconnect various signaling pathways into human and computer readable network maps. These maps can then be used to classify and study individual components involved in a particular phenomenon. Apart from transcriptomics, several individual gene studies have resulted in adding to our knowledge of key components that are involved in a signaling pathway. It therefore becomes imperative to take into account of these studies also, while constructing our network maps to highlight the interconnectedness of the entire signaling pathways and the role of that particular individual protein in the pathway. This collection of articles will contain a collection of pioneering work done by scientists working in regulatory signaling networks and the use of large scale gene expression and omics data. The distinctive features of this book would be: Act a single source of information to understand the various components of different signaling network (roadmap of biochemical pathways, the nature of a molecule of interest in a particular pathway, etc.), Serve as a platform to highlight the key findings in this highly volatile and evolving field, and Provide answers to various techniques both related to microarray and cell signaling to the readers.

Understanding Cell Signaling

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Release : 2021
Genre : Cellular signal transduction
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Book Rating : 036/5 ( reviews)

Understanding Cell Signaling - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Understanding Cell Signaling write by James Ellsworth Ferrell. This book was released on 2021. Understanding Cell Signaling available in PDF, EPUB and Kindle. "All living cells continually detect and respond to external signals. This is true of prokaryotes, whether they are living alone or in biofilms, and it is even more manifestly true in multicellular eukaryotes, where communication between cells and coordination of the cells' behavior enables the organism to function as a unified whole. In large multicellular organisms like us humans, cells receive signals from their immediate neighbors through short-range signals like neurotransmitters and cell-surface molecules. They receive signals from more distant neighbors via longer-range diffusible molecules like morphogens, and from still-more distant neighbors by means of hormones that flow through the circulatory system. And they receive signals from the outside world via sense organs. Cells also monitor their own internal status, and there is a great deal of overlap between the cellular components involved in cell-cell communication and internal monitoring"--

Immuno Systems Biology

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Release : 2013-10-01
Genre : Medical
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Book Rating : 909/5 ( reviews)

Immuno Systems Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Immuno Systems Biology write by Kumar Selvarajoo. This book was released on 2013-10-01. Immuno Systems Biology available in PDF, EPUB and Kindle. Immuno Systems Biology aims to study the immune system in the more integrated manner on how cells and molecules participate at different system levels to the immune function. Through this book Kumar Selvarajoo introduces to physicists, chemists, computer scientists, biologists and immunologists the idea of an integrated approach to the understanding of mammalian immune system. Geared towards a researcher with limited immunological and computational analytical experience, the book provides a broad overview to the subject and some instruction in basic computational, theoretical and experimental approaches. The book links complex immunological processes with computational analysis and emphasizes the importance of immunology to the mammalian system.