T-Cell Trafficking - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook T-Cell Trafficking write by George Edward Rainger. This book was released on 2017-03-28. T-Cell Trafficking available in PDF, EPUB and Kindle. This second edition provides updated and new chapters on T-Cell trafficking. In addition to detailed experimental procedures, the interested reader will find informative introductory chapters on the relevance of T-Cell trafficking in thymic population and maturation, traffic through secondary lymphoid organs during ‘physiological’ resolving inflammation and during immune responses, as well as T-Cell trafficking in chronic inflammatory diseases. Importantly, chapters cover methods from in silico modeling of cellular interactions, in vitro adhesion assays, through ex vivo functional assays to integrated intravital modeling of T-Cell trafficking through organs. Written in the highly successful Methods in Molecular Biology series format, each methods chapter includes a short introduction to the topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, T-Cell Trafficking: Methods and Protocols, Second Edition aims to be an essential point of reference for those new to the field of T-Cell trafficking, or to those looking to expand their technical capabilities.
Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy write by Emmanuel Donnadieu. This book was released on 2016-08-30. Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy available in PDF, EPUB and Kindle. This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
T-Cell Trafficking
T-Cell Trafficking - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook T-Cell Trafficking write by Federica M. Marelli-Berg. This book was released on 2017-04-30. T-Cell Trafficking available in PDF, EPUB and Kindle. In the last decade, a large number of major discoveries have shed light on the molecular mechanisms of lymphocyte migration and the anatomy of immune responses. In T-Cell Trafficking: Methods and Protocols, expert researchers explore how the development of novel and cutting-edge techniques, particularly in the field of real-time imaging and genetic manipulation, have led to an increased understanding of lymphocyte trafficking. Written by internationally recognized experts in their respective fields, chapters provide state-of-the-art protocols to study lymphocyte migration and T-cell: endothelial cell interactions in vitro, address various approaches used for direct visualization of the development of the lymphoid system, lymphocyte recirculation, and effector responses in experimental models in vivo, and explore lymphocyte migration and inflammation in the human system. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Innovative and highly practical, T-Cell Trafficking: Methods and Protocols is an essential manual for newcomers in this ever-expanding and exciting area of research, as well as a valuable addition to more specialized laboratories.
Protein Trafficking in Neurons
Protein Trafficking in Neurons - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Protein Trafficking in Neurons write by Andrew J. Bean. This book was released on 2006-10-27. Protein Trafficking in Neurons available in PDF, EPUB and Kindle. The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Trafficking in Neurons examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. The book is divided into seven sections that review mechanisms of protein transport, the role of protein trafficking in synapse formation, exo- and endocytosis, transport of receptors, trafficking of ion channels and transporters, comparison of trafficking mechanisms in neuronal vs. non-neuronal cell types, and the relationship between trafficking and neuronal diseases such as Alzheimer's, Huntington's and Prion Diseases. - Provides a comprehensive examination of membrane/protein movement in neuronal function - Sections on synapse development, synaptic transmission, and the role of trafficking in neurological disease - Includes a focus on Molecular Mechanisms - Illustrated with color summary pictures - The only book examining protein trafficking and its functional implications, written by leaders in the field
Trafficking Inside Cells
Trafficking Inside Cells - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Trafficking Inside Cells write by Nava Segev. This book was released on 2010-05-30. Trafficking Inside Cells available in PDF, EPUB and Kindle. This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.
