Test No. 443: Extended One-Generation Reproductive Toxicity Study

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Release : 2011-07-28
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Book Rating : 559/5 ( reviews)

Test No. 443: Extended One-Generation Reproductive Toxicity Study - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Test No. 443: Extended One-Generation Reproductive Toxicity Study write by OECD. This book was released on 2011-07-28. Test No. 443: Extended One-Generation Reproductive Toxicity Study available in PDF, EPUB and Kindle. This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study

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Release : 1983-05-26
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Book Rating : 842/5 ( reviews)

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study write by OECD. This book was released on 1983-05-26. OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study available in PDF, EPUB and Kindle. This Test Guideline for reproduction testing is designed to provide general information concerning the effects of a test substance (Solid, liquid, gas or vapour) on male and female reproductive performance. The test substance is administered orally ...

How ECHA Identifies the Design for the Extended One-generation Reproductive Toxicity Study (EOGRTS) Under Dossier Evaluation

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Release : 2016
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Book Rating : 271/5 ( reviews)

How ECHA Identifies the Design for the Extended One-generation Reproductive Toxicity Study (EOGRTS) Under Dossier Evaluation - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook How ECHA Identifies the Design for the Extended One-generation Reproductive Toxicity Study (EOGRTS) Under Dossier Evaluation write by . This book was released on 2016. How ECHA Identifies the Design for the Extended One-generation Reproductive Toxicity Study (EOGRTS) Under Dossier Evaluation available in PDF, EPUB and Kindle. The extended one-generation reproductive toxicity study (EOGRTS) is a modular test method where breeding and assessment of a second filial (F2) generation and testing for developmental neurotoxicity (DNT) and developmental immunotoxicity (DIT) are distinct and independent modules. The appropriate study design needs to be defined, justified and documented. Specification is required for the: - length of the premating exposure duration and dose level selection, - need to extend Cohort 1B to include the mating of F1 animals to produce a F2 generation, - need to include the DNT cohorts, and - need to include the DIT cohort. The information sources the Agency considers crucial for defining the EOGRTS design are discussed in this document in addition to aspects of triggering the study itself and its various designs.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study

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Release : 2018-06-27
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Book Rating : 372/5 ( reviews)

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study write by OECD. This book was released on 2018-06-27. OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study available in PDF, EPUB and Kindle. This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity

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Release : 2001-01-22
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Book Rating : 869/5 ( reviews)

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity write by OECD. This book was released on 2001-01-22. OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity available in PDF, EPUB and Kindle. This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive systems, and on the growth and ...