The Chemistry of β-Lactams - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Chemistry of β-Lactams write by M.I. Page. This book was released on 2012-12-06. The Chemistry of β-Lactams available in PDF, EPUB and Kindle. It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
Antibiotic Drug Resistance
Antibiotic Drug Resistance - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Antibiotic Drug Resistance write by José-Luis Capelo-Martínez. This book was released on 2019-09-24. Antibiotic Drug Resistance available in PDF, EPUB and Kindle. This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Synthesis of β-Lactam Antibiotics
Synthesis of β-Lactam Antibiotics - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Synthesis of β-Lactam Antibiotics write by Alle Bruggink. This book was released on 2011-06-27. Synthesis of β-Lactam Antibiotics available in PDF, EPUB and Kindle. Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Beta-Lactams
Beta-Lactams - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Beta-Lactams write by Bimal K. Banik. This book was released on 2017-05-11. Beta-Lactams available in PDF, EPUB and Kindle. This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications
Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications write by Hartmut Derendorf. This book was released on 2019-07-11. Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications available in PDF, EPUB and Kindle. Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.
