The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

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Release : 2013-02-19
Genre : Science
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Book Rating : 678/5 ( reviews)

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging write by Andre S. Merbach. This book was released on 2013-02-19. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging available in PDF, EPUB and Kindle. Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

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Release : 2001-04-09
Genre : Science
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Book Rating : 786/5 ( reviews)

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging write by André E. Merbach. This book was released on 2001-04-09. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging available in PDF, EPUB and Kindle. There has been a huge increase in the use of MRI and contrast agents in medicine in recent years as evidenced by a big increase in the number of hospitals with MRI machines and the ever-increasing number of examinations using contrast agents. Contrast agents have revolutionized the use of Magnetic Resonance Imaging (MRI) in medical diagnostics, allowing doctors to distinguish between normal and abnormal tissues and ultimately improving prognosis for the patient. This monograph covers all aspects of production, use, operating mechanisms and theory of these diagnostic agents, used to produce high contrast images in MRI. It will therefore be unique resource for what is currently a very active domain of research both in universities and in industry. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging is a comprehensive treatise: * written by the most active scientists in the field of contrast agents for medical MRI - from both university and industrial backgrounds * covering the topic from every angle from synthesis to safety considerations * invaluable to physicists, chemists, biologists as well as physicians * the first in-depth coverage of this topic

Medical Imaging Contrast Agents: A Clinical Manual

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Release : 2021-08-24
Genre : Medical
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Book Rating : 560/5 ( reviews)

Medical Imaging Contrast Agents: A Clinical Manual - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Medical Imaging Contrast Agents: A Clinical Manual write by Sukru Mehmet Erturk. This book was released on 2021-08-24. Medical Imaging Contrast Agents: A Clinical Manual available in PDF, EPUB and Kindle. This volume highlights and broadens our understanding of the correct use and the possible contraindications of contrast agents applied in radiology. Written by experts in the field, it not only focuses on the chemistry, physiochemical properties and pharmacokinetics of both iodinated and gadolinium-containing contrast agents, but also on the relevant safety issues such as frequency of their short- and long-term side effects and ways to avoid them nephrotoxicity risk related to the iodinated contrast agents NSF (nephrogenic systemic fibrosis) accumulation of gadolinium in the brain use of contrast agents in pediatric patients and pregnancy It also includes essential data on the use of contrast agents, such as scanning protocols, in the context of various clinical conditions. This comprehensive manual addresses all professionals involved in radiological imaging and is an invaluable tool for radiologists and technologists, as well as for residents and clinicians.

Contrast Agents I

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Release : 2003-07-01
Genre : Science
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Book Rating : 33X/5 ( reviews)

Contrast Agents I - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Contrast Agents I write by Werner Krause. This book was released on 2003-07-01. Contrast Agents I available in PDF, EPUB and Kindle. Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1].

Electron Paramagnetic Resonance Spectroscopy

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Release : 2020-02-03
Genre : Science
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Book Rating : 630/5 ( reviews)

Electron Paramagnetic Resonance Spectroscopy - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Electron Paramagnetic Resonance Spectroscopy write by Patrick Bertrand. This book was released on 2020-02-03. Electron Paramagnetic Resonance Spectroscopy available in PDF, EPUB and Kindle. Although originally invented and employed by physicists, electron paramagnetic resonance (EPR) spectroscopy has proven to be a very efficient technique for studying a wide range of phenomena in many fields, such as chemistry, biochemistry, geology, archaeology, medicine, biotechnology, and environmental sciences. Acknowledging that not all studies require the same level of understanding of this technique, this book thus provides a practical treatise clearly oriented toward applications, which should be useful to students and researchers of various levels and disciplines. In this book, the principles of continuous wave EPR spectroscopy are progressively, but rigorously, introduced, with emphasis on interpretation of the collected spectra. Each chapter is followed by a section highlighting important points for applications, together with exercises solved at the end of the book. A glossary defines the main terms used in the book, and particular topics, whose knowledge is not required for understanding the main text, are developed in appendices for more inquisitive readers.