Silva's Diagnostic Renal Pathology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Silva's Diagnostic Renal Pathology write by Xin J. Zhou. This book was released on 2017-03-02. Silva's Diagnostic Renal Pathology available in PDF, EPUB and Kindle. An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.
Cystogenesis
Cystogenesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Cystogenesis write by Jong Hoon Park. This book was released on 2016-10-12. Cystogenesis available in PDF, EPUB and Kindle. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
The Cystic Kidney
The Cystic Kidney - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Cystic Kidney write by K.D. Gardner. This book was released on 2012-12-06. The Cystic Kidney available in PDF, EPUB and Kindle. This is a book about renal cysts and cystic kidneys. Its contributors have created a resource of current information in a field that once aroused only curiosity, but that now stands at the leading edge of molecular nephrology. Its authorship includes 'oldtimers', who bring the wisdom of experience, and 'newcomers', whose presence attests to the contributions made by the investigative and technological advances of the past decade. Its text is organized to carry the reader from renal cyst to cystic renal disease. Each of its chapters defines or explores a challenge or an advance. Cells that line renal cysts are diverse in structure, type, and perhaps function. The cysts themselves lie within an interstitium that is not normal and may influence cyst development and growth. Experimental analogs of human disease offer increasing opportunities to basic researchers to examine, in sequence and under controlled circumstances, those events that favor nephron dilation, cyst growth and ultimate renal failure.
Ferri's Clinical Advisor 2020 E-Book
Ferri's Clinical Advisor 2020 E-Book - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Ferri's Clinical Advisor 2020 E-Book write by Fred F. Ferri. This book was released on 2019-06-01. Ferri's Clinical Advisor 2020 E-Book available in PDF, EPUB and Kindle. Significantly updated with the latest developments in diagnosis and treatment recommendations, Ferri's Clinical Advisor 2020 features the popular "5 books in 1" format to organize vast amounts of information in a clinically relevant, user-friendly manner. This efficient, intuitive format provides quick access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, and laboratory tests – all reviewed by experts in key clinical fields. Updated algorithms, along with hundreds of new figures, tables, and boxes, ensure that you stay current with today's medical practice. - Contains significant updates throughout, covering all aspects of current diagnosis and treatment. - Features 27 all-new topics including chronic traumatic encephalopathy, medical marijuana, acute respiratory failure, gallbladder carcinoma, shift work disorder, radial tunnel syndrome, fertility preservation in women, fallopian tube cancer, primary chest wall cancer, large-bowel obstruction, inguinal hernia, and bundle branch block, among others. - Includes a new appendix covering Physician Quality Reporting System (PQRS) Measures. - Provides current ICD-10 insurance billing codes to help expedite insurance reimbursements. - Patient Teaching Guides for many of the diseases and disorders are included, most available in both English and Spanish versions, which can be downloaded and printed for patients.
Manual of Pediatric Nephrology
Manual of Pediatric Nephrology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Manual of Pediatric Nephrology write by Kishore D. Phadke. This book was released on 2013-12-13. Manual of Pediatric Nephrology available in PDF, EPUB and Kindle. This manual will meet the everyday needs of the wide range of medical professionals who play a role in the treatment of children referred to hospital because of renal disease. It is an easy-to-use, portable guide that will assist pediatricians, residents, and trainees in making prompt first-level management decisions. It will also prove invaluable for the adult nephrologists who care for children in many developing countries, and will serve as a teaching guide for experts when training non-subspecialists. Individual sections are devoted to the evaluation of renal disease; fluid, electrolyte, and acid-base disorders; glomerular diseases; tubular disorders; congenital, inherited, and urological disorders; consequences of renal disease; and miscellaneous topics. The text is in a bulleted format with tables and algorithms wherever possible, making it straightforward and easy to read. An appendix includes further important information such as normal values, drug dosages, and drug nephrotoxicity.
