The Eukaryotic RNA Exosome - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Eukaryotic RNA Exosome write by John LaCava. This book was released on 2019-11-25. The Eukaryotic RNA Exosome available in PDF, EPUB and Kindle. This volume provides a cross-section of RNA exosome research protocols, applied to a diversity of model organisms. Chapters guide readers through methods that e.g. delineate eukaryotic exosomes’ origins in prokaryotes, probe its RNA substrates, adapter complexes and macromolecular interaction of networks, and establish critical structural-function relationships. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Eukaryotic RNA Exosome: Methods and Protocols aims to ensure successful results in the further study of this vital field.
RNA Exosome
RNA Exosome - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook RNA Exosome write by Torben Heick Jensen. This book was released on 2011-06-29. RNA Exosome available in PDF, EPUB and Kindle. The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.
RNA Metabolism and Gene Expression in Archaea
RNA Metabolism and Gene Expression in Archaea - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook RNA Metabolism and Gene Expression in Archaea write by Béatrice Clouet-d'Orval. This book was released on 2017-10-28. RNA Metabolism and Gene Expression in Archaea available in PDF, EPUB and Kindle. This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and maturation of RNAs, the function of small non-coding RNAs and the CRISPR-Cas defense system. While Archaea have long been considered exotic microbial extremophiles, they are now increasingly being recognized as important model microorganisms for the study of molecular mechanisms conserved across the three domains of life, and with regard to the relevance of similarities and differences to eukaryotes and bacteria. This unique book offers a valuable resource for all readers interested in the regulation of gene expression in Archaea and RNA metabolism in general.
Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis
Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis write by . This book was released on 2012-11-27. Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis available in PDF, EPUB and Kindle. This special volume of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This thematic volume discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis.
Mesenchymal Stem Cell Derived Exosomes
Mesenchymal Stem Cell Derived Exosomes - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mesenchymal Stem Cell Derived Exosomes write by Yaoliang Tang. This book was released on 2015-09-02. Mesenchymal Stem Cell Derived Exosomes available in PDF, EPUB and Kindle. Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. - Introduces the MSC-exosome mediated cell-cell communication - Covers the major functional benefits in current MSC-derived exosome studies - Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies
