The Mouse in Biomedical Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Mouse in Biomedical Research write by . This book was released on 2006-12-15. The Mouse in Biomedical Research available in PDF, EPUB and Kindle. Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.
The Mouse in Biomedical Research: Diseases
The Mouse in Biomedical Research: Diseases - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Mouse in Biomedical Research: Diseases write by Henry L. Foster. This book was released on 1982. The Mouse in Biomedical Research: Diseases available in PDF, EPUB and Kindle.
The Mouse in Biomedical Research
The Mouse in Biomedical Research - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Mouse in Biomedical Research write by Henry Foster. This book was released on 1981-01-01. The Mouse in Biomedical Research available in PDF, EPUB and Kindle. The Mouse in Biomedical Research, Volume I: History, Genetics, and Wild Mice focuses on the utility of the mouse as a laboratory animal in biomedical research. A historical perspective on the development and origins of the laboratory and wild mouse is given. The diversity of inbred strains of mice as well as the methods of developing and the genetic monitoring and testing of these strains are discussed. This volume consists of 14 chapters and begins with an overview of mice of the genus Mus and problems concerning evolution within the genus. The following chapters focus on taxonomy, nomenclature, and breeding systems, together with recombinant inbred and congenic resistant mouse strains. Methods of constructing, testing, and monitoring strains are described. Congenic strains, gene mapping, cytogenetics, and murine experimental studies are also considered, along with the histocompatibility-2 complex and radiation genetics. The final chapter is devoted to the pharmacogenetics of the laboratory mouse, paying particular attention to intoxication and detoxication pathways, genetically determined differences in xenobiotic metabolism, and pharmacogenetic polymorphisms. This book will be a useful reference for investigators using mice in many areas of research.
Making Mice
Making Mice - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Making Mice write by Karen Rader. This book was released on 2004-03-21. Making Mice available in PDF, EPUB and Kindle. Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research. Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice. This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.
Basic Science Methods for Clinical Researchers
Basic Science Methods for Clinical Researchers - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Basic Science Methods for Clinical Researchers write by Morteza Jalali. This book was released on 2017-03-31. Basic Science Methods for Clinical Researchers available in PDF, EPUB and Kindle. Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow's clinician scientists and future leaders in discovery science. - Serves as a helpful guide for clinical researchers who lack a conventional science background - Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms - Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data - Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)
