Optical Polarization in Biomedical Applications

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Release : 2006-10-12
Genre : Science
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Book Rating : 210/5 ( reviews)

Optical Polarization in Biomedical Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Optical Polarization in Biomedical Applications write by Valery V. Tuchin. This book was released on 2006-10-12. Optical Polarization in Biomedical Applications available in PDF, EPUB and Kindle. Optical Polarization in Biomedical Applications introduces key developments in optical polarization methods for quantitative studies of tissues, while presenting the theory of polarization transfer in a random medium as a basis for the quantitative description of polarized light interaction with tissues. This theory uses the modified transfer equation for Stokes parameters and predicts the polarization structure of multiple scattered optical fields. The backscattering polarization matrices (Jones matrix and Mueller matrix) important for noninvasive medical diagnostic are introduced. The text also describes a number of diagnostic techniques such as CW polarization imaging and spectroscopy, polarization microscopy and cytometry. As a new tool for medical diagnosis, optical coherent polarization tomography is analyzed. The monograph also covers a range of biomedical applications, among them cataract and glaucoma diagnostics, glucose sensing, and the detection of bacteria.

Polarized Light in Biomedical Imaging and Sensing

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Release : 2022-11-14
Genre : Technology & Engineering
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Book Rating : 419/5 ( reviews)

Polarized Light in Biomedical Imaging and Sensing - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Polarized Light in Biomedical Imaging and Sensing write by Jessica C. Ramella-Roman. This book was released on 2022-11-14. Polarized Light in Biomedical Imaging and Sensing available in PDF, EPUB and Kindle. This book focuses on biomedical applications of polarized light, covering instrumentation and modeling specific to the field. This will be the first book, written by leading researchers in the field, to tackle this important topic. Readers will learn the fundamentals of polarized light transport and how to develop instrumentation for clinical and preclinical studies. They will also become familiar with the latest advancement in data analysis and image processing for a variety of medical applications. The book is dedicated specifically to the biomedical community, including scientists, engineers, and physicians working on the development of instrumentation for clinical and preclinical use. Emphasizes biomedical imaging and sensing; Describes new computational approaches with examples; Provides detailed descriptions of novel instrumentation.

The Use of Polarized Light for Biomedical Applications

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Release : 2003
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The Use of Polarized Light for Biomedical Applications - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Use of Polarized Light for Biomedical Applications write by Justin Shekwoga Baba. This book was released on 2003. The Use of Polarized Light for Biomedical Applications available in PDF, EPUB and Kindle. Polarized light has the ability to increase the specificity of the investigation of biomedical samples and is finding greater utilization in the fields of medical diagnostics, sensing, and measurement. In particular, this dissertation focuses on the application of polarized light to address a major obstacle in the development of an optical based polarimetric non-invasive glucose detector that has the potential to improve the quality of life and prolong the life expectancy of the millions of people afflicted with the disease diabetes mellitus. By achieving the mapping of the relative variations in rabbit corneal birefringence, it is hoped that the understanding of the results contained herein will facilitate the development of techniques to eliminate the effects of changing corneal birefringence on polarimetric glucose measurement through the aqueous humor of the eye. This dissertation also focuses on the application of polarized light to address a major downside of cardiovascular biomechanics research, which is the utilization of toxic chemicals to prepare samples for histological examination. To this end, a polarization microscopy image processing technique is applied to non-stained cardiovascular samples as a means to eliminate, for certain cardiac samples, the necessity for staining using toxic chemicals. The results from this work have the potential to encourage more investigators to join the field of cardiac biomechanics, which studies the remodeling processes responsible for cardiovascular diseases such as myocardial infarct (heart attacks) and congestive heart failure. Cardiovascular disease is epidemic, particularly amongst the population group older than 65 years, and the number of people affected by this disease is expected to increase appreciably as the baby boomer generation transitions into this older, high risk population group. A better understanding of the responsible mechanisms for cardiac tissue remodeling will facilitate the development of better prevention and treatment regimens by improving the early detection and diagnosis of this disease.

The Application of Polarized Light to Biomedical Diagnostics and Monitoring

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Release : 2000
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The Application of Polarized Light to Biomedical Diagnostics and Monitoring - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Application of Polarized Light to Biomedical Diagnostics and Monitoring write by Brent Duane Cameron. This book was released on 2000. The Application of Polarized Light to Biomedical Diagnostics and Monitoring available in PDF, EPUB and Kindle.

Development and Use of Polarized Light Methods to Assess Structure and Composition of Biological Tissue

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Release : 2011
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Book Rating : 803/5 ( reviews)

Development and Use of Polarized Light Methods to Assess Structure and Composition of Biological Tissue - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Development and Use of Polarized Light Methods to Assess Structure and Composition of Biological Tissue write by Michael F. G. Wood. This book was released on 2011. Development and Use of Polarized Light Methods to Assess Structure and Composition of Biological Tissue available in PDF, EPUB and Kindle. The use of polarized light for characterization of biological tissues has received increased attention in recent years due to the wealth of information available in the interactions of polarized light with tissue and the noninvasive nature of optical radiation. While the depolarizing effects of multiple scattering complicate the use of polarimetry in tissue, many biological constituents affect the polarization of light such as collagen, muscle fibers, and glucose. Thus, if the effects of scattering can be accounted for--or utilized in the analysis--polarized light can potentially be used as a probe of tissue status.This thesis presents advancements in the techniques for the simulation of polarized light in tissue-simulating media, and explores two biomedical applications. Previous Monte Carlo models for simulation of polarized light propagation in tissue-simulating media do not include the effects of birefringence and optical activity, two polarizing effects of useful diagnostic potential. To overcome this limitation, our model was extended to include both these effects simultaneously, and then experimentally validated using a novel polarization phantom system. The use of polarized light for characterization of the myocardium, and specifically towards monitoring stem cell regenerative treatments of myocardial infarction, was investigated experimentally as a novel application for polarimetry. The potential for this technique is based on the changes in myocardial structure that occur with infarction and subsequent regeneration, and the associated changes in tissue birefringence. The use of polarized light for noninvasive tissue analyte monitoring, particularly glucose, was also investigated based on the optical activity exhibited by many tissue analytes due to their chiral structure. In this study, a novel combined optical polarization and intensity approach was developed and tested on Monte Carlo simulated data. The studies presented in thesis introduce new methods for polarization simulation and analysis in biological tissue and demonstrate potential for polarimetry in monitoring myocardial regeneration and noninvasive measurements of tissue analytes.