Theories of Population Variation in Genes and Genomes

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Release : 2014-11-23
Genre : Science
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Book Rating : 890/5 ( reviews)

Theories of Population Variation in Genes and Genomes - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Theories of Population Variation in Genes and Genomes write by Freddy Bugge Christiansen. This book was released on 2014-11-23. Theories of Population Variation in Genes and Genomes available in PDF, EPUB and Kindle. This textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. Contains up-to-date treatment of key areas in classical and modern theoretical population genetics Provides in-depth coverage of coalescent theory Discusses genomic effects of selection Gives examples from empirical population genetics Incorporates figures, diagrams, and boxed features throughout Includes end-of-chapter exercises Speaks to a wide range of students in biology, bioinformatics, and biostatistics

Theories of Population Variation in Genes and Genomes

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Release : 2007
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Book Rating : /5 ( reviews)

Theories of Population Variation in Genes and Genomes - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Theories of Population Variation in Genes and Genomes write by Freddy Bugge Christiansen. This book was released on 2007. Theories of Population Variation in Genes and Genomes available in PDF, EPUB and Kindle.

Theoretical Aspects of Population Genetics. (MPB-4), Volume 4

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Release : 2020-03-31
Genre : Science
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Book Rating : 098/5 ( reviews)

Theoretical Aspects of Population Genetics. (MPB-4), Volume 4 - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Theoretical Aspects of Population Genetics. (MPB-4), Volume 4 write by Motoo Kimura. This book was released on 2020-03-31. Theoretical Aspects of Population Genetics. (MPB-4), Volume 4 available in PDF, EPUB and Kindle. To show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations. R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution. For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included.

Population Genetics and Microevolutionary Theory

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Release : 2021-05-04
Genre : Science
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Book Rating : 364/5 ( reviews)

Population Genetics and Microevolutionary Theory - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Population Genetics and Microevolutionary Theory write by Alan R. Templeton. This book was released on 2021-05-04. Population Genetics and Microevolutionary Theory available in PDF, EPUB and Kindle. Population Genetics and Microevolutionary Theory Explore the fundamentals of the biological implications of population genetic theory In the newly revised Second Edition of Population Genetics and Microevolutionary Theory, accomplished researcher and author Alan R. Templeton delivers a fulsome discussion of population genetics with coverage of exciting new developments in the field, including new discoveries in epigenetics and genome-wide studies. The book prepares students to successfully apply population genetics analytical tools by providing a solid foundation in microevolutionary theory. The book emphasizes that population structure forms the underlying template upon which quantitative genetics and natural selection operate and is a must-read for future population and evolutionary geneticists and those who wish to work in genetic epidemiology or conservation biology. You’ll learn about a wide array of topics, including quantitative genetics, the interactions of natural selection with other evolutionary forces, and selection in heterogeneous environments and age-structured populations. Appendices that cover genetic survey techniques and probability and statistics conclude the book. Readers will also benefit from the inclusion of: A thorough introduction to population genetics, including the scope of the subject, its premises, and the Hardy-Weinberg Model of Microevolution An exploration of systems of mating, including a treatment of the use of runs of homozygosity to show pedigree inbreeding in distant ancestors A practical discussion of genetic drift, including the use of effective sizes in conservation biology (with a discussion of African rhinos as an example) A concise examination of coalescence, including a treatment of the infinite sites model Perfect for graduate students in genetics and evolutionary biology programs and advanced undergraduate biology majors, Population Genetics and Microevolutionary Theory will also earn a place in the libraries of students taking courses in conservation biology, human genetics, bioinformatics, and genomics.

Population Genetics, Molecular Evolution, and the Neutral Theory

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Release : 1994
Genre : Science
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Book Rating : 633/5 ( reviews)

Population Genetics, Molecular Evolution, and the Neutral Theory - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Population Genetics, Molecular Evolution, and the Neutral Theory write by Motoo Kimura. This book was released on 1994. Population Genetics, Molecular Evolution, and the Neutral Theory available in PDF, EPUB and Kindle. One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.