Topology in Molecular Biology

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Release : 2006-10-26
Genre : Science
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Book Rating : 583/5 ( reviews)

Topology in Molecular Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Topology in Molecular Biology write by Michael I. Monastyrsky. This book was released on 2006-10-26. Topology in Molecular Biology available in PDF, EPUB and Kindle. Providing a course of modern topology intended for biologists and physicists, this book presents a class of results in molecular biology for which topological methods and ideas are important. These include: the large-scale conformation properties of DNA; computational methods; the structure of proteins; and other problems in molecular biology.

Discrete and Topological Models in Molecular Biology

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Release : 2013-12-23
Genre : Computers
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Book Rating : 937/5 ( reviews)

Discrete and Topological Models in Molecular Biology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Discrete and Topological Models in Molecular Biology write by Nataša Jonoska. This book was released on 2013-12-23. Discrete and Topological Models in Molecular Biology available in PDF, EPUB and Kindle. Theoretical tools and insights from discrete mathematics, theoretical computer science, and topology now play essential roles in our understanding of vital biomolecular processes. The related methods are now employed in various fields of mathematical biology as instruments to "zoom in" on processes at a molecular level. This book contains expository chapters on how contemporary models from discrete mathematics – in domains such as algebra, combinatorics, and graph and knot theories – can provide perspective on biomolecular problems ranging from data analysis, molecular and gene arrangements and structures, and knotted DNA embeddings via spatial graph models to the dynamics and kinetics of molecular interactions. The contributing authors are among the leading scientists in this field and the book is a reference for researchers in mathematics and theoretical computer science who are engaged with modeling molecular and biological phenomena using discrete methods. It may also serve as a guide and supplement for graduate courses in mathematical biology or bioinformatics, introducing nontraditional aspects of mathematical biology.

DNA Topology

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Release : 2005
Genre : Science
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Book Rating : 097/5 ( reviews)

DNA Topology - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook DNA Topology write by Andrew D. Bates. This book was released on 2005. DNA Topology available in PDF, EPUB and Kindle. "A key aspect of DNA is its ability to form a variety of structures, this book explains the origins and importance of such structures"--Provided by publisher.

DNA Topoisomerase Protocols

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Release : 1999-03-23
Genre : Medical
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DNA Topoisomerase Protocols - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook DNA Topoisomerase Protocols write by Mary-Ann Bjornsti. This book was released on 1999-03-23. DNA Topoisomerase Protocols available in PDF, EPUB and Kindle. DNA Topoisomerase Protocols, I: DNA Topology and Enzymes brings together an unprecedented collection of cutting-edge experimental protocols for investigating DNA structure, topology, and DNA topoisomerase function. Described by expert experimentalists who have perfected the techniques, these unfailingly reproducible methods utilize new approaches to study changes in DNA topology (linking number, knotting, catenation, and relaxation) and DNA structure (bending), as well as to assess chromosome structure through FLP-mediated recombination and to analyze bacterial nucleoid structure. State-of-the-art protocols also detail the expression and purification of bacterial, viral, and eukaryotic DNA topoisomerases from a variety of sources, including baculovirus, and bacterial, yeast and mammalian expression systems. A companion volume, DNA Topoisomerase Protocols, v. 2: Enzymology and Drugs, provides detailed protocols to study the catalytic activities of DNA topoisomerases, as well as their specific interactions with topoisomerase-targeted antitumor and antibacterial drugs. DNA Topoisomerase Protocols, I: DNA Topology and Enzymes will be of immense value to the many basic scientists and clinicians who want better to understand and to exploit proficiently the wealth of recent discoveries about chromatin structure and its relation to gene expression, about DNA topoisomerases as the targets of antitumor and antibacterial agents, and about DNA repair.

Knots, Molecules, and the Universe

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Release : 2015-12-22
Genre : Mathematics
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Book Rating : 351/5 ( reviews)

Knots, Molecules, and the Universe - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Knots, Molecules, and the Universe write by Erica Flapan. This book was released on 2015-12-22. Knots, Molecules, and the Universe available in PDF, EPUB and Kindle. This book is an elementary introduction to geometric topology and its applications to chemistry, molecular biology, and cosmology. It does not assume any mathematical or scientific background, sophistication, or even motivation to study mathematics. It is meant to be fun and engaging while drawing students in to learn about fundamental topological and geometric ideas. Though the book can be read and enjoyed by nonmathematicians, college students, or even eager high school students, it is intended to be used as an undergraduate textbook. The book is divided into three parts corresponding to the three areas referred to in the title. Part 1 develops techniques that enable two- and three-dimensional creatures to visualize possible shapes for their universe and to use topological and geometric properties to distinguish one such space from another. Part 2 is an introduction to knot theory with an emphasis on invariants. Part 3 presents applications of topology and geometry to molecular symmetries, DNA, and proteins. Each chapter ends with exercises that allow for better understanding of the material. The style of the book is informal and lively. Though all of the definitions and theorems are explicitly stated, they are given in an intuitive rather than a rigorous form, with several hundreds of figures illustrating the exposition. This allows students to develop intuition about topology and geometry without getting bogged down in technical details.