Toxic Phosphorus Esters

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Release : 2013-10-22
Genre : Science
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Book Rating : 939/5 ( reviews)

Toxic Phosphorus Esters - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Toxic Phosphorus Esters write by Richard D. O'Brien. This book was released on 2013-10-22. Toxic Phosphorus Esters available in PDF, EPUB and Kindle. Toxic Phosphorus Esters: Chemistry, Metabolism, and Biological Effects aims to become a source book on organophosphate research and show how the understanding of the events following organophosphate poisoning of animals can be understood in terms of events at the molecular level. The manuscript first offers information on nonenzymic reactions and the reaction with cholinesterase in vitro. Discussions focus on hydrolysis, isomerization, oxidation, phosphorylation of the enzyme, and selectivity for different cholinesterases. The text then examines enzymic degradation and activation in vitro, effects in mammals, and effects on isolated whole tissues. The publication ponders on the effects in insects and plants, including results of poisoning, metabolism, resistance, antagonism and synergism, and phytotoxicity. The text also reviews selective toxicity, as well as excretion and storage, metabolism, design of new selective compounds, and nature of the target. The manuscript is a dependable reference for readers interested in the composition, reactions, and effects of toxic phosphorus esters.

TOXIC PHOSPHORUS ESTERS: CHEMISTRY, METABOLISM, AND BIOLOGICAL EFFECTS.

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Release : 1960
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Book Rating : /5 ( reviews)

TOXIC PHOSPHORUS ESTERS: CHEMISTRY, METABOLISM, AND BIOLOGICAL EFFECTS. - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook TOXIC PHOSPHORUS ESTERS: CHEMISTRY, METABOLISM, AND BIOLOGICAL EFFECTS. write by RD. OBRIEN. This book was released on 1960. TOXIC PHOSPHORUS ESTERS: CHEMISTRY, METABOLISM, AND BIOLOGICAL EFFECTS. available in PDF, EPUB and Kindle.

Studies on Microbial Degradation of Toxic Phosphorus Esters. Part 1. Detoxification of O, O-Dimethyl-O-(2-carbomethoxy-1-methylvinyl) Phosphate by Soil Bacteria

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Release : 1969
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Book Rating : /5 ( reviews)

Studies on Microbial Degradation of Toxic Phosphorus Esters. Part 1. Detoxification of O, O-Dimethyl-O-(2-carbomethoxy-1-methylvinyl) Phosphate by Soil Bacteria - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Studies on Microbial Degradation of Toxic Phosphorus Esters. Part 1. Detoxification of O, O-Dimethyl-O-(2-carbomethoxy-1-methylvinyl) Phosphate by Soil Bacteria write by B. C. Wolverton. This book was released on 1969. Studies on Microbial Degradation of Toxic Phosphorus Esters. Part 1. Detoxification of O, O-Dimethyl-O-(2-carbomethoxy-1-methylvinyl) Phosphate by Soil Bacteria available in PDF, EPUB and Kindle. In an attempt to find a new method for detoxifying cholinesterase-inhibiting, organophosphorus compounds, studies were undertaken to isolate bacteria capable of degrading O, O-dimethyl-O-(2-carbomethoxy-1-methylvinyl) phosphate (Phosdrin). Degradation of the insecticide was determined by gas chromatography, while decreased toxicity was confirmed by measuring cholinesterase activity with a recording pH stat. Of the thirty cultures screened, two showed 80-90% degradation of the original 20 ppm Phosdrin in 10 days, with a corresponding decrease in toxicity. One of the cultures was isolated from soil collected on Eglin Air Force Base, Florida, and the other as a laboratory contaminant. The bacteria were identified as two different strains of Bacillus megaterium. (Author).

The Manufacture and Use of Selected Aryl and Alkyl Aryl Phosphate Esters, Task I

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Release : 1976
Genre : Esters
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The Manufacture and Use of Selected Aryl and Alkyl Aryl Phosphate Esters, Task I - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Manufacture and Use of Selected Aryl and Alkyl Aryl Phosphate Esters, Task I write by United States. Environmental Protection Agency. Office of Toxic Substances. This book was released on 1976. The Manufacture and Use of Selected Aryl and Alkyl Aryl Phosphate Esters, Task I available in PDF, EPUB and Kindle.

Toxicological Risks of Selected Flame-Retardant Chemicals

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Release : 2000-07-06
Genre : Nature
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Book Rating : 938/5 ( reviews)

Toxicological Risks of Selected Flame-Retardant Chemicals - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Toxicological Risks of Selected Flame-Retardant Chemicals write by National Research Council. This book was released on 2000-07-06. Toxicological Risks of Selected Flame-Retardant Chemicals available in PDF, EPUB and Kindle. Ignition of upholstered furniture by small open flames from matches, cigarette lighters, and candles is one of the leading causes of residential-fire deaths in the United States. These fires accounted for about 16% of civilian fire deaths in 1996. On average, each year since 1990, about 90 deaths (primarily of children), 440 injuries, and property losses amounting to 50 million dollars have resulted from fires caused by the ignition of upholstered furniture by small open flames. Certain commercial seating products (such as aircraft and bus seats) are subject to flammability standards and sometimes incorporate FR-treated upholstery cover materials, but there is no federal-government requirement for residential upholstered furniture, and it is generally not treated with FR chemicals. It is estimated that less than 0.2% of all U.S. residential upholstery fabric is treated with flame-retardant (FR) chemicals. The Consumer Product Safety Act of 1972 created the U.S. Consumer Product Safety Commission (CPSC) as an independent federal regulatory agency whose mission is to protect the public from unreasonable risks of injury and death associated with consumer products. CPSC also administers the Flammable Fabrics Act, under which it regulates flammability hazards and the Federal Hazardous Substances Act (FHSA), which regulates hazardous substances including chemicals. In 1993, the National Association of State Fire Marshals petitioned CPSC to issue a performance-based flammability standard for upholstered furniture to reduce the risk of residential fires. The Commission granted that portion of the petition relating to small open flame ignition risks. In response to concerns regarding the safety of FR chemicals, Congress, in the fiscal year 1999 appropriations report for CPSC, requested that the National Research Council conduct an independent study of the health risks to consumers posed by exposure to FR chemicals that are likely to be used in residential upholstered furniture to meet a CPSC standard. The National Research Council assigned the project to the Committee on Toxicology (COT) of the Commission on Life Sciences' Board on Environmental Studies and Toxicology. COT convened the Subcommittee on Flame-Retardant Chemicals, which prepared this report. Subcommittee members were chosen for their recognized expertise in toxicology, pharmacology, epidemiology, chemistry, exposure assessment, risk assessment, and biostatistics. Toxicological Risks of Selected Flame-Retardant Chemicals is organized into 18 chapters and two appendices. Chapter 2 describes the risk assessment process used by the subcommittee in determining the risk associated with potential exposure to the various FR chemicals. Chapter 3 describes the method the subcommittee used to measure and estimate the intensity, frequency, extent, and duration of human exposure to FR chemicals. Chapters 4-19 provide the subcommittee's review and assessment of health risks posed by exposure to each of the 16 FR chemicals. Data gaps and research needs are provided at the end of these chapters.