Toxicity Testing for Assessment of Environmental Agents - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Toxicity Testing for Assessment of Environmental Agents write by National Research Council. This book was released on 2006-05-07. Toxicity Testing for Assessment of Environmental Agents available in PDF, EPUB and Kindle. Toxicity testing in laboratory animals provides much of the information used by the Environmental Protection Agency (EPA) to assess the hazards and risks associated with exposure to environmental agents that might harm public health or the environment. The data are used to establish maximum acceptable concentrations of environmental agents in drinking water, set permissible limits of exposure of workers, define labeling requirements, establish tolerances for pesticides residues on food, and set other kinds of limits on the basis of risk assessment. Because the number of regulations that require toxicity testing is growing, EPA called for a comprehensive review of established and emerging toxicity-testing methods and strategies. This interim report reviews current toxicity-testing methods and strategies and near-term improvements in toxicity-testing approaches proposed by EPA and others. It identifies several recurring themes and questions in the various reports reviewed. The final report will present a long-range vision and strategic plan to advance the practices of toxicity testing and human health assessment of environmental contaminants.
Toxicity Testing in the 21st Century
Toxicity Testing in the 21st Century - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Toxicity Testing in the 21st Century write by National Research Council. This book was released on 2007-10-05. Toxicity Testing in the 21st Century available in PDF, EPUB and Kindle. Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Toxicity Testing in the 21st Century
Toxicity Testing in the 21st Century - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Toxicity Testing in the 21st Century write by National Research Council. This book was released on 2007-11-05. Toxicity Testing in the 21st Century available in PDF, EPUB and Kindle. Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
In Vitro Toxicity Testing Of Environmental Agents, Current and Future Possibilities
In Vitro Toxicity Testing Of Environmental Agents, Current and Future Possibilities - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook In Vitro Toxicity Testing Of Environmental Agents, Current and Future Possibilities write by Alan R. Kolber. This book was released on 1983-01-01. In Vitro Toxicity Testing Of Environmental Agents, Current and Future Possibilities available in PDF, EPUB and Kindle.
In Vitro Toxicity Testing of Environmental Agents
In Vitro Toxicity Testing of Environmental Agents - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook In Vitro Toxicity Testing of Environmental Agents write by Alan R. Kolber. This book was released on 1983. In Vitro Toxicity Testing of Environmental Agents available in PDF, EPUB and Kindle. These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa tion and ideas on the current approaches (both scientific and po litical) for toxic assessment of environmental agents. The poten tial health effects of these compounds as well as future needs in the environmental research field were discussed. The scientific content of the conference seminars included an overview of the various cellular, subcellular, organ, animal, and genetic systems which have been used to assess the health effects of environmental agents. The scientific principles behind short term assays and an evaluation of their applicability to health effects monitoring and analysis were investigated. Included among major topics were: (1) the biochemistry and pharmacology of selected environmental agents; (2) molecular mechanisms of car cinogenesis, mutagenesis, and transformation; (3) bacterial muta genesis and toxicity; (4) mammalian cell mutagenesis, toxicity, and transformation; (5) in vitro carcinogens and mutagens; (6) teratogenic and other developmental toxic effects; and (7) the development of short-term neuro-behavioral toxicity assays.
