TRP Channels as Therapeutic Targets - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook TRP Channels as Therapeutic Targets write by Arpad Szallasi. This book was released on 2015-04-09. TRP Channels as Therapeutic Targets available in PDF, EPUB and Kindle. TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings. Contains comprehensive coverage of TRP channels as therapeutic targets, from emerging clinical indications to completed clinical trials Discusses TRP channels as validated targets, ranging from obesity and diabetes through cancer and respiratory disorders, kidney diseases, hypertension, neurodegenerative disorders, and more Provides critical analysis of the complications and side effects that have surfaced during clinical trials, offering evidence-based suggestions for overcoming them
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades write by Wolfgang B. Liedtke, MD, PH.D.. This book was released on 2006-09-29. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades available in PDF, EPUB and Kindle. Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Mammalian Transient Receptor Potential (TRP) Cation Channels
Mammalian Transient Receptor Potential (TRP) Cation Channels - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mammalian Transient Receptor Potential (TRP) Cation Channels write by Bernd Nilius. This book was released on 2014-06-24. Mammalian Transient Receptor Potential (TRP) Cation Channels available in PDF, EPUB and Kindle. In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
Transient Receptor Potential (TRP) Channels
Transient Receptor Potential (TRP) Channels - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Transient Receptor Potential (TRP) Channels write by Veit Flockerzi. This book was released on 2007-02-07. Transient Receptor Potential (TRP) Channels available in PDF, EPUB and Kindle. This volume provides up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression.
Itch
Itch - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Itch write by E. Carstens. This book was released on 2014-02-25. Itch available in PDF, EPUB and Kindle. Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
