TRP Channels as Therapeutic Targets - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook TRP Channels as Therapeutic Targets write by Arpad Szallasi. This book was released on 2015-04-09. TRP Channels as Therapeutic Targets available in PDF, EPUB and Kindle. TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings. Contains comprehensive coverage of TRP channels as therapeutic targets, from emerging clinical indications to completed clinical trials Discusses TRP channels as validated targets, ranging from obesity and diabetes through cancer and respiratory disorders, kidney diseases, hypertension, neurodegenerative disorders, and more Provides critical analysis of the complications and side effects that have surfaced during clinical trials, offering evidence-based suggestions for overcoming them
TRP Channels as Therapeutic Targets
TRP Channels as Therapeutic Targets - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook TRP Channels as Therapeutic Targets write by Arpad Szallasi. This book was released on 2024-08-26. TRP Channels as Therapeutic Targets available in PDF, EPUB and Kindle. TRP Channels as Therapeutic Targets, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. The Editor lined up a team of worldwide experts in academia and corporate R&D to provide diverse views into these promising drug development targets. Following the research development happened in the past ten years, since the first edition published, the revision includes seven new chapters. All remaining chapters are completely updated. New topics included in the book are TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. TRP Channels as Therapeutic Targets, Second Edition is a reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline, will find in this book their biologic principles of action. Presents the perspectives of several life science research specialties on the topic Provides a comprehensive picture of the TRP field, from TRP channel dysfunction through TRP drug discovery and development to clinical trials and everyday medical practice Represents an updated and complete reference
Innovative Medicine
Innovative Medicine - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Innovative Medicine write by Kazuwa Nakao. This book was released on 2015-10-13. Innovative Medicine available in PDF, EPUB and Kindle. This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts
Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts write by Susan M. Huang (Ed.). This book was released on . Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts available in PDF, EPUB and Kindle.
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades write by Wolfgang B. Liedtke, MD, PH.D.. This book was released on 2006-09-29. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades available in PDF, EPUB and Kindle. Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
