Metallo-Drugs: Development and Action of Anticancer Agents - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Metallo-Drugs: Development and Action of Anticancer Agents write by Astrid Sigel. This book was released on 2018-02-05. Metallo-Drugs: Development and Action of Anticancer Agents available in PDF, EPUB and Kindle. Volume 18, entitled Metallo-Drugs: Development and Action of Anticancer Agents of the series Metal Ions in Life Sciences centers on biological, medicinal inorganic chemistry. The serendipitous discovery of the antitumor activity of cis-diamminodichloroplatinum(II) (cisplatin) by Barnett Rosenberg in the 1960s is a landmark in metallodrug-based chemotherapy. The success of cisplatin in the clinic, followed by oxaliplatin and carboplatin, along with their drawbacks relating mainly to resistance development and severe toxicity, initiated research on polynuclear platinum complexes and on Pt(IV) complexes as prodrugs. Furthermore, the indicated shortcomings led to the exploration of other transition and main group metal ions, among them Ru(II/III), Au(I/III), Ti(IV), V(IV/V), and Ga(III) including also the essential metal ions Fe(II/III), Cu(I/II), and Zn(II). Ionic as well as covalent and non-covalent interactions between structurally very different complexes and biomolecules like nucleic acids, proteins, and carbohydrates are studied and discussed with regard to their possible anticancer actions. Hence, MILS-18 summarizes the research at the forefront of medicinal inorganic chemistry, including studies on the next-generation, tailor-made anticancer drugs. All this and more is treated in an authoritative and timely manner in the 17 stimulating chapters of this book, written by 39 internationally recognized experts from 10 nations (from the US via Europe to China and Australia). The impact of this vibrant research area is manifested by more than 2700 references, nearly 150 illustrations (more than half in color) and several comprehensive tables. Metallo-Drugs: Development and Action of Anticancer Agents is an essential resource for scientists working in the wide range from enzymology, material sciences, analytical, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that it also provides excellent information for teaching.
The Rebbe's Children
The Rebbe's Children - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Rebbe's Children write by Shmuli Zalmanov. This book was released on 2015-02-02. The Rebbe's Children available in PDF, EPUB and Kindle. In this collection of insights from the Lubavitcher Rebbe, compiled from a variety of letters, public addresses and private audiences, the Rebbe provides practical guidelines and advice on a myriad of topics concerning and addressed to Yeshiva students who are attending Chabad-Lubavitch Yeshivas. The book's title - 'The Rebbe's Children' - is inspired by the Rebbe lovingly referring to these Chabad students (otherwise known as 'Tmimim') as his own children. This is apparent in the enthusiastic spirit and fatherly affection exhibited in this compilation.
Unlocking the Torah Text: Vayikra
Unlocking the Torah Text: Vayikra - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Unlocking the Torah Text: Vayikra write by Shmuel Goldin. This book was released on 2007. Unlocking the Torah Text: Vayikra available in PDF, EPUB and Kindle. An In-Depth Journey Into the Weekly Parsha.
The Call of Freedom
The Call of Freedom - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Call of Freedom write by Karen Rabbi Gluckstern-Reiss. This book was released on 2000. The Call of Freedom available in PDF, EPUB and Kindle. Sourcebook that includes important concepts to remain informed about the State of Israel.
Living Waters
Living Waters - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Living Waters write by Betsalel Philip Edwards. This book was released on 2001-03-01. Living Waters available in PDF, EPUB and Kindle. Living Waters - The Mei HaShiloach: A Commentary on the Torah by Rabbi Mordechai Yosef of Isbitza (1800-1854) is the collected teachings on the Torah by the hasidic master Rabbi Mordechai Yosef of Isbitza. Born in Poland to a rabbinic family, Reb Yosef was a student of Reb Simcha Bunem of Pshiske. It was from Reb Bunem that he received the well springs of the teachings of the Baal Shem Tov, the founder of the hasidic movement.
