Vascular Development

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Release : 2007-08-20
Genre : Science
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Book Rating : 429/5 ( reviews)

Vascular Development - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Vascular Development write by Derek J. Chadwick. This book was released on 2007-08-20. Vascular Development available in PDF, EPUB and Kindle. The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.

Vascular Biology of the Placenta

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Release : 2017-06-23
Genre : Medical
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Book Rating : 514/5 ( reviews)

Vascular Biology of the Placenta - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Vascular Biology of the Placenta write by Yuping Wang. This book was released on 2017-06-23. Vascular Biology of the Placenta available in PDF, EPUB and Kindle. The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

The Endothelium

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Release : 2011
Genre : Science
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Book Rating : 230/5 ( reviews)

The Endothelium - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook The Endothelium write by Michel Félétou. This book was released on 2011. The Endothelium available in PDF, EPUB and Kindle. The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Molecular Biology of The Cell

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Release : 2002
Genre : Cytology
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Book Rating : 183/5 ( reviews)

Molecular Biology of The Cell - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Biology of The Cell write by Bruce Alberts. This book was released on 2002. Molecular Biology of The Cell available in PDF, EPUB and Kindle.

Mechanisms of Vascular Disease

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Release : 2011
Genre : Medical
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Book Rating : 009/5 ( reviews)

Mechanisms of Vascular Disease - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Mechanisms of Vascular Disease write by Robert Fitridge. This book was released on 2011. Mechanisms of Vascular Disease available in PDF, EPUB and Kindle. New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.