Vascular Engineering

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Release : 2016-03-17
Genre : Medical
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Book Rating : 017/5 ( reviews)

Vascular Engineering - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Vascular Engineering write by Kazuo Tanishita. This book was released on 2016-03-17. Vascular Engineering available in PDF, EPUB and Kindle. This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and explains how the impact of related disease conditions — atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction — has generated a focus on developing expertise to both maintain and treat the vascular system. As a comprehensive book in this expanding area, Vascular Engineering serves as a valuable resource for clinicians as well as academics and professionals working in biophysics, biomedical engineering, and nano and microrheology. Graduate students in these subject areas will also find this volume insightful.

Tissue Engineering of Prosthetic Vascular Grafts

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Release : 1999
Genre : Medical
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Book Rating : /5 ( reviews)

Tissue Engineering of Prosthetic Vascular Grafts - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Tissue Engineering of Prosthetic Vascular Grafts write by Peter Paul Zilla. This book was released on 1999. Tissue Engineering of Prosthetic Vascular Grafts available in PDF, EPUB and Kindle.

Tissue-Engineered Vascular Grafts

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Release : 2020-08-21
Genre : Science
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Book Rating : 352/5 ( reviews)

Tissue-Engineered Vascular Grafts - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Tissue-Engineered Vascular Grafts write by Beat H. Walpoth. This book was released on 2020-08-21. Tissue-Engineered Vascular Grafts available in PDF, EPUB and Kindle. Cardiovascular diseases are still the leading cause of death in developed countries. Revascularization procedures such as coronary artery and peripheral bypass grafts, as well as access surgery represent a 2$ billion market yearly for the US alone. Despite intense research over many decades, no clinically suitable, shelf-ready, synthetic, vascular, small-caliber graft exists. There is therefore still a quest for such a clinical vascular prosthesis for surgical revascularization procedures and access surgery. Many approaches have been tried and are currently under investigation with promising results. These range from acellular and cell-based, stable or bio-degradable, synthetic scaffolds to biological or decellularized grafts, not forgetting self-assembly technologies for in vitro or in vivo VTE. All these approaches can be further enhanced by functionalization, e.g. with growth factors and drug elution. This updatable book aims to cover all the relevant aspects of Vascular Tissue Engineering (VTE) and novel alternatives to develop vascular grafts for clinical applications. The chapters in this book cover different aspects of manufacturing scaffolds with various polymers, mechanical characteristics, degradation rates, decellularization techniques, cell sheet assembly, 3-D printing and autologous mandril-based VTE. All the necessary in vitro tests such as biocompatibility and thrombogenicity are reviewed. Pre-clinical assessment of in vivo experimental models include patency, compliance, intimal hyperplasia, inflammatory reaction, cellular ingrowth and remodeling. Finally, early clinical trials will be periodically updated regarding results, regulatory aspects and post-marketing quality assessment. Furthermore, the reader should get an insight into various approaches, technologies and methods to better understand the complexity of blood surface and cell interactions in VTE. Translational research has yielded early human applications clearly showing the enormous need of research in the field to provide better solutions for our patients and this continuously updated book will hopefully become a reference in the field for life sciences.

Vascular Tissue Engineering

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Release : 2022-10-02
Genre : Science
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Book Rating : 106/5 ( reviews)

Vascular Tissue Engineering - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Vascular Tissue Engineering write by Feng Zhao. This book was released on 2022-10-02. Vascular Tissue Engineering available in PDF, EPUB and Kindle. This volume explores the latest techniques used to study the field of tissue engineered vascular grafts (TEVGs). The chapters in this book cover a wide array of topics such as deriving vascular cells from monocytes and induced pluripotent stem cells; engineering vascular grafts using various biomaterials and stem cells, stem cell-derived, or primary vascular cells; biomaterial modification by anticoagulation molecules; vascular bioengineering technologies such as 3D bioprinting; and fabrication of TEVGs with different geometry and multiphase structures. This book also features protocols for grafting and evaluation of vascular grafts in animal models, vascular imaging in animals, and the quantification of blood vessel permeability. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vascular Tissue Engineering: Methods and Protocols is a valuable resource for biomedical engineers, cell biologists, vascular surgeons, doctors, and nurses.

Fluid Mechanics for Cardiovascular Engineering

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Release : 2021-10-28
Genre : Technology & Engineering
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Book Rating : 436/5 ( reviews)

Fluid Mechanics for Cardiovascular Engineering - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Fluid Mechanics for Cardiovascular Engineering write by Gianni Pedrizzetti. This book was released on 2021-10-28. Fluid Mechanics for Cardiovascular Engineering available in PDF, EPUB and Kindle. This book provides a guiding thread between the distant fields of fluid mechanics and clinical cardiology. Well rooted in the science of fluid dynamics, it drives the reader across progressively more realistic scenarios up to the complexity of routine medical applications. Based on the author’s 25 years of collaborations with cardiologists, it helps engineers learn communicating with clinicians, yet maintaining the rigor of scientific disciplines. This book starts with a description of the fundamental elements of fluid dynamics in large blood vessels. This is achieved by introducing a rigorous physical background accompanied by examples applied to the circulation, and by presenting classic and recent results related to the application of fluid dynamics to the cardiovascular physiology. It then explores more advanced topics for a physics-based understanding of phenomena effectively encountered in clinical cardiology. It stands as an ideal learning resource for physicists and engineers working in cardiovascular fluid dynamics, industry engineers working on biomedical/cardiovascular technology, and students in bio-fluid dynamics. Written with a concise style, this textbook is accessible to a broad readership, including students, physical scientists and engineers, offering an entry point into this multi-disciplinary field. It includes key concepts exemplified by illustrations using cutting-edge imaging, references to modelling and measurement technologies, and includes unique original insights.