Voltage Gated Sodium Channels - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Voltage Gated Sodium Channels write by Peter C. Ruben. This book was released on 2014-04-15. Voltage Gated Sodium Channels available in PDF, EPUB and Kindle. A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.
Molecular Biology of The Cell
Molecular Biology of The Cell - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Molecular Biology of The Cell write by Bruce Alberts. This book was released on 2002. Molecular Biology of The Cell available in PDF, EPUB and Kindle.
Voltage-Gated Ion Channels as Drug Targets
Voltage-Gated Ion Channels as Drug Targets - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Voltage-Gated Ion Channels as Drug Targets write by David J. Triggle. This book was released on 2006-08-21. Voltage-Gated Ion Channels as Drug Targets available in PDF, EPUB and Kindle. Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades write by Wolfgang B. Liedtke, MD, PH.D.. This book was released on 2006-09-29. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades available in PDF, EPUB and Kindle. Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Calcium Entry Channels in Non-Excitable Cells
Calcium Entry Channels in Non-Excitable Cells - read free eBook in online reader or directly download on the web page. Select files or add your book in reader. Download and read online ebook Calcium Entry Channels in Non-Excitable Cells write by Juliusz Ashot Kozak. This book was released on 2017-07-14. Calcium Entry Channels in Non-Excitable Cells available in PDF, EPUB and Kindle. Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
